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Polycystic Ovary Syndrome (PCOS) affects 6%-15% of women of reproductive age, causing symptoms like acne and hair loss, and increasing the risk of type 2 diabetes and heart disease; it's managed through diet, exercise, and medications like Metformin and hormonal contraceptives.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The document suggests more research is needed to understand skin conditions related to toothpaste and other treatments.

Targeting the Smoothened receptor shows promise for treating certain cancers.

High levels of prolactin in the blood can be linked to widespread hair loss.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Long-term fluticasone treatment does not harm the immune system in horses with heaves.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

A woman with low thyroid function did not lose her hair during chemotherapy, possibly because her hair follicles were less affected by the treatment.

A new method was developed to accurately detect and measure 47 different drug ingredients in various products.

Physalis fruits have medicinal properties that can help treat various diseases and have anti-inflammatory, antioxidant, antibacterial, and antitumor effects.

Dr. Mario Lacouture recommends preventive and specific treatments for skin side effects caused by EGFR inhibitors to improve patients' quality of life.

New treatments are making advanced prostate cancer management more complex but also more hopeful.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Blocking JAK-STAT signaling can lead to hair growth.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

No treatment fully prevents hair loss from chemotherapy yet.

High doses of cyproterone acetate are linked to an increased risk of developing meningioma.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Bimatoprost can cause excessive eyelash growth.