Search

everythinglearnresearchcommunity

for

Search:↓

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

Minoxidil's absorption is too variable for it to be a reliable reference drug.

Method detects finasteride in plasma at very low concentrations.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.

Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Method detects finasteride in plasma and semen with high sensitivity and accuracy.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

New method detects finasteride in plasma quickly and accurately without clean-up.

Reliable method detects finasteride in human plasma at low doses.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Risk analysis is important for safely adjusting pharmaceutical formulas while maintaining their quality and effectiveness.

Hair follicles can be used to quickly assess drug effects in cancer treatment.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.