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The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

PLD is an effective and safer alternative for treating breast cancer.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Neurosteroids show promise for treating epilepsy and more research is needed.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.

Deoxycholic acid is effective for reducing chin fat but can cause side effects and serious complications, so careful patient evaluation is needed.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

New acne treatments show promise as alternatives to traditional therapies.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.