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BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

New nanocarriers improve drug delivery for disease treatment.

Teriflunomide effectively reduces relapse rates and disease progression in multiple sclerosis but is not safe for use during pregnancy.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The new patch for treating mouth sores releases medicine slowly, sticks well, and helps healing without the side effects of current creams.

The MXD/24HA salt is more effective for hair growth than raw MXD.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Chitosan-decorated finasteride nanosystems improve skin retention and could be a better treatment for hair loss.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Some skin medications can have harmful interactions with the COVID-19 drug nirmatrelvir-ritonavir, but not with molnupiravir.

Microneedles are a promising method for drug delivery, offering efficient and convenient alternatives with fewer side effects.

Ginsenoside Rg4 from ginseng may help hair growth by activating certain cell signals.

MG53 helps reduce skin damage caused by nitrogen mustard.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Solidified SEDDS improve drug stability and bioavailability better than liquid SEDDS.

Finasteride-loaded nanogels are effective, safe, and improve drug absorption through the skin.

The nanocrystalline suspension effectively delivers dutasteride over time with minimal inflammation.

Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.

The hydrogel made of chitosan, HPMC, and insulin speeds up wound healing and could be a new dressing, especially for diabetics.

Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

New therapies are being developed that target integrin pathways to treat various diseases.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.