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PLD is an effective and safer alternative for treating breast cancer.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

New treatments for male hypogonadism are effective and should be personalized.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Birth control pills increase the risk of blood clots, especially within the first year and with certain types.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.

Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.

Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

New drug delivery methods can make natural compounds more effective and stable.

Scalp cooling is largely ineffective in preventing hair loss from breast cancer chemotherapy.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.