research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
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research Drug Safety Evaluation of Exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
research Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs
Nanoporous silica entrapped lipid-drug complexes significantly improve the solubility and absorption of drugs that don't dissolve well in water.
research Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain
Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
research Clinically Relevant Chemotherapy Interactions with Complementary and Alternative Medicines in Patients with Cancer
Some herbal medicines can interfere with chemotherapy, affecting treatment and causing side effects.
research Issues in the Treatment of Epilepsy
Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.
research Costunolide: A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential
Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
research A New Topical Formulation of Minoxidil and Finasteride Improves Hair Growth in Men with Androgenetic Alopecia
MorrF improves hair growth better than minoxidil alone.
research Sublingual Tofacitinib for Alopecia Areata: A Roll-Over Pilot Clinical Trial and Analysis of Pharmacokinetics
The trial showed that a new under-the-tongue treatment for severe hair loss was somewhat effective in a small group of people.
research (1R,2S)-4-(2-Cyano-Cyclohexyl-Oxy)-2-Trifluoromethyl-Benzonitrile, A Potent Androgen Receptor Antagonist For Stimulating Hair Growth And Reducing Sebum Production
The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
research Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum Debile Extract as Functional Food and Nutraceutical Ingredients
Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.
research The Selective Androgen Receptor Modulator GTx-024 (Enobosarm) Improves Lean Body Mass and Physical Function in Healthy Elderly Men and Postmenopausal Women: Results of a Double-Blind, Placebo-Controlled Phase II Trial
Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
research Associations Of Prenatal And Postnatal Exposure To Perfluoroalkyl Substances With Pubertal Development And Reproductive Hormones In Females And Males: The Home Study
PFAS exposure in adolescence may delay puberty in females.
research Progesterone, Neurosteroids, and the Hormonal Basis of Catamenial Epilepsy
Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study
New method measures finasteride in plasma, finds two formulations bioequivalent.
research Teriflunomide in Multiple Sclerosis: An Update
Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.
research Topical Finasteride Dose Evaluation for Treatment of Androgenetic Alopecia Using Computer Simulations
Topical finasteride at 0.25% is effective and has fewer side effects than oral finasteride for hair loss.
research Finasteride
Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
research Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica
Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.
research Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients
The study suggests hormonal factors may play a role in Frontal Fibrosing Alopecia and that treatments like oral antiandrogens and steroids could be beneficial.
research Enabling Finasteride 1 mg Users to Further Improve Hair Pattern: A Randomized, Double-Blind, Placebo-Controlled Trial of a Novel Product
The new topical product combined with finasteride significantly increased hair thickness without side effects.
research High-Performance Liquid Chromatographic Method for the Determination of Finasteride in Human Plasma at Therapeutic Doses
Reliable method detects finasteride in human plasma at low doses.
research The Pharmacology of Methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching
New method detects finasteride in plasma quickly and accurately without clean-up.
research A Phase I Study of Topical Tempol for the Prevention of Alopecia Induced by Whole Brain Radiotherapy
Tempol is safe and may prevent hair loss from brain radiotherapy.
research In Vitro Biotransformation of Finasteride in Rat Hepatic Microsomes: Isolation and Characterization of Metabolites
research ST008 Male Androgenetic Alopecia: A New Treatment Paradigm
New treatment improves male hair loss.
research Tolerance and Safety Profile of Sublingual Minoxidil in the Treatment of Androgenic Alopecia
Sublingual minoxidil is a safe and effective treatment for hair loss, especially in women.
research Topical Cetirizine 1% for Treatment of Androgenetic Alopecia
Topical cetirizine 1% increases hair density and may be a promising treatment for hair loss.
research The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers
This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.