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Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Micelles can change cetirizine's ionization, affecting its effectiveness in treatments.

Both drugs lower DHT levels, with GI198745 being more effective.

Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.

Potential new drugs for treating PCOS were identified.

The nanocrystalline suspension effectively delivers dutasteride over time with minimal inflammation.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Computational methods can speed up and improve the development and safety of herbal drugs.

The model and estimator can predict drug exposure in kidney transplant patients well.

Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

Finasteride may improve prostate cancer treatment outcomes.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

The best starting dose for a new finasteride injection is 16.80 mg.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Older patients with advanced kidney cancer can be managed with a drug called Sunitinib.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.

The normal human prostate does not significantly affect blood DHT levels.

Finasteride dosages should be adjusted based on CYP3A5 genotype and liver function to avoid side effects.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

The Gas-Antisolvent process can be effectively modeled and optimized to create Finasteride, a hair growth drug.

Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.

Taking five small dutasteride capsules is the same as taking one larger capsule.

Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.