research Relationship Between Contact Time of Applied Dose and Percutaneous Absorption of Minoxidil From a Topical Solution
Longer contact time increases minoxidil absorption, but doesn't affect metabolism.
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research Topical Formulations Containing Finasteride: In Vitro Permeation/Penetration Study and In Vivo Pharmacokinetics in Hairless Rat
Finasteride cream helps hair growth with less side effects.
research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research Preparation and Evaluation of Minoxidil Gels for Topical Application in Alopecia
Minoxidil gels with higher concentrations are more stable and effective for treating hair loss.
research Three Isostructural Solvates of Finasteride and Their Solid-State Characterization
Three new finasteride solvates found, change forms under different drying conditions.
research Radioimmunoassay of Minoxidil in Human Serum
Minoxidil levels measured in human blood.
research Structural Characterization and Dissolution Profile of Mycophenolic Acid Cocrystals
The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.
research Rapid Determination of Minoxidil in Human Plasma Using Ion-Pair HPLC
Quick method to measure minoxidil in blood, accurate and useful for labs.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research Alginate-Based Hydrogel Containing Minoxidil/Hydroxypropyl-β-Cyclodextrin Inclusion Complex for Topical Alopecia Treatment
A new gel containing minoxidil can treat hair loss effectively, potentially reducing side effects and improving treatment.
research LC-APCI+-MS/MS Method for the Analysis of Ten Hormones and Two Endocannabinoids in Plasma and Hair from Mice with Different Gut Microbiota
The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.
research Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability
Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
research Phytochemical, Toxicological and Pharmacological Studies of Asiasari Radix et Rhizoma: A Review
Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.
research Preparation, Evaluation, and Hair Growth Stimulating Activity of Herbal Hair Oil
Herbal hair oil with 7.5% amla, hibiscus, brahmi, and methi promotes hair growth as effectively as minoxidil.
research A Rapid, Simple, Specific Liquid Chromatographic–Electrospray Mass Spectrometry Method for the Determination of Finasteride in Human Plasma and Its Application to Pharmacokinetic Study
Method measures finasteride in plasma, suitable for pharmacokinetic studies.
research Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders
New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
research Preformulation Studies of Finasteride to Design Matrix Systems for Topical Delivery
research Topical Formulations Containing Finasteride: Determination of Finasteride Penetration into Hair Follicles Using the Differential Stripping Technique
Formulation P-08-016 better targets hair follicles for baldness treatment.
research Comprehensive Spectroscopic Characterization of Finasteride Polymorphic Forms: Does Form X Exist?
Three finasteride forms exist; "form X" doesn't.
research Development of a Doxazosin and Finasteride Transdermal System for Combination Therapy of Benign Prostatic Hyperplasia
Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.
research Evaluation of Hair Growth Promoting Activity of Musa Paradisiaca Unripe Fruit Extract
Unripe banana extract may promote hair growth similar to minoxidil.
research Ex-Vivo Measurement of Scalp Follicular Infundibulum Delivery of Zinc Pyrithione and Climbazole from an Anti-Dandruff Shampoo
The method shows that zinc pyrithione and climbazole from anti-dandruff shampoo effectively reach the scalp.
research Quality Evaluation of the Finasteride Polymorphic Forms I and II in Capsules
Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
research Analysis of the Pretreatment Effect of Ethanol on the Stratum Corneum- and Hair Follicular-Penetration of Drugs Using the Hair Follicle-Plugging Method
The study investigated the impact of ethanol (EtOH) pretreatment on drug penetration through the skin and hair follicles using the hair follicle-plugging method. In vitro experiments with excised pig ear skin and four model drugs showed that hair follicle-plugging reduced the skin permeation of ionized lidocaine (LC), fluorescein (FL), and fluorescein isothiocyanate (FITC)-dextran 4 kDa (FD-4). Specifically, hair follicle-plugging prevented the permeation of FL and FD-4 in EtOH-pretreated skin but did not affect isosorbide mononitrate (ISMN). The effect on ionized LC varied with different pretreatment conditions. The findings suggested that EtOH pretreatment significantly influenced the aqueous pathways in the stratum corneum and hair follicles.
research LC-MS Bioanalytical Method for Simultaneous Determination of Latanoprost and Minoxidil in the Skin
Method measures latanoprost and minoxidil in skin accurately and precisely.
research Selective and Rapid Determination of Tadalafil and Finasteride Using Solid Phase Extraction by High Performance Liquid Chromatography and Tandem Mass Spectrometry
Quick, selective detection of tadalafil and finasteride in human plasma developed.
research A Review on Constituents, Pharmacological Activities, and Medicinal Uses of Glycyrrhiza Glabra
Glycyrrhiza glabra has various medicinal properties, including antibacterial and antioxidant effects.
research A Study on the Extracts of Cuscuta Reflexa Roxb. in the Treatment of Cyclophosphamide-Induced Alopecia
Cuscuta reflexa extracts helped regrow hair in rats with drug-induced hair loss.
research A Quantitative Ultra-Performance Liquid Chromatography High-Resolution Mass Spectrometry Analysis of Steroids from Human Scalp Hair
The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.
research Efficacy of Cetirizine 1% Versus Minoxidil 5% Topical Solution in the Treatment of Male Alopecia: A Randomized, Single-Blind Controlled Study
Cetirizine 1% helps hair growth in men with no major side effects, but minoxidil 5% works better.