19 citations,
October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.
19 citations,
September 2002 in “Acta dermato-venereologica” Topical tacrolimus did not regrow hair in alopecia universalis patients.
18 citations,
February 2015 in “Acta Crystallographica Section D: Structural Biology” The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.
18 citations,
March 2014 in “Drug Development and Industrial Pharmacy” New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
18 citations,
July 2009 in “Drug Metabolism and Disposition” Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.
17 citations,
March 2020 in “Frontiers in Chemistry” Compounds from the plant Mammea siamensis may help treat hair loss.
17 citations,
June 2012 in “European journal of medicinal chemistry” New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
17 citations,
August 2011 in “Current Medicinal Chemistry” New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
15 citations,
November 2020 in “Pharmaceutics” Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.
15 citations,
July 2016 in “Biochemical Journal” Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
14 citations,
December 2011 in “Archives of Dermatological Research” Phyto-vesicles of β-sitosterol may effectively treat hair loss.
14 citations,
August 2009 in “Cancer epidemiology” AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.
13 citations,
January 2015 in “Molecular Pharmaceutics” Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.
13 citations,
October 2012 in “Free Radicals and Antioxidants” The red Hibiscus rosa-sinensis flower has the highest antioxidant activity.
12 citations,
March 2020 in “Journal of Bioactive and Compatible Polymers” Nanoparticles show potential for controlled release of hair loss drugs, improving treatment effectiveness.
12 citations,
January 2018 in “Journal of Drug Delivery Science and Technology” The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
12 citations,
November 2003 in “Journal of the American Academy of Dermatology” Topical diphencyprone helped regrow hair in mice and rats with a condition similar to human hair loss.
12 citations,
May 2001 in “British journal of dermatology/British journal of dermatology, Supplement” A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.
11 citations,
September 2020 in “Journal of Cosmetic Dermatology” Silver nanoparticles can significantly promote hair growth.
11 citations,
April 2019 in “International Journal of Molecular Sciences” Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.
11 citations,
January 2017 in “Biochemical and biophysical research communications” 1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.
11 citations,
January 2006 in “Drug development and industrial pharmacy” Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.
10 citations,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
10 citations,
October 2015 in “Medicina Clínica (english Edition)” Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.
10 citations,
March 2015 in “Journal of dermatology” The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.
9 citations,
June 2021 in “International Journal of Pharmaceutics” Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
9 citations,
January 1999 in “Journal of Liquid Chromatography & Related Technologies” Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.
9 citations,
March 1989 in “The BMJ” Adding diltiazem to a beta blocker can cause dangerously slow heart rates.
8 citations,
January 2021 in “Pharmaceutics” Nanoporous silica entrapped lipid-drug complexes significantly improve the solubility and absorption of drugs that don't dissolve well in water.
8 citations,
March 2018 in “Journal of Drug Delivery Science and Technology” Itraconazole-loaded nanoparticles are more effective and less toxic for treating fungal infections than conventional oral itraconazole.