research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
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research Recent Updates on Wnt Signaling Modulators: A Patent Review (2014-2020)
New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
research Spontaneous Cutaneous Adverse Drug Reaction Reports: An Analysis of a 10-Year Dataset in Singapore
In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.
research Assessment of Prescribing Information for Generic Drugs Manufactured in the Middle East and Marketed in Saudi Arabia
Generic drug inserts in Saudi Arabia often have inaccurate information, needing better regulation and quality control.
research Development and Ex-Vivo Skin Permeation Studies of Finasteride–Poly(Lactic Acid-Co-Glycolic Acid) and Minoxidil–Chitosan Nanoparticulate Systems
Nanoparticles show potential for controlled release of hair loss drugs, improving treatment effectiveness.
research Sexual Problems of Men With Androgenic Alopecia Treated With 5-Alpha Reductase Inhibitors
Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.
research Microemulsions as Carriers for Therapeutic Molecules
Microemulsions could improve how drugs are delivered and absorbed in the body.
research Establishment of an Evaluation Method to Detect Drug Distribution in Hair Follicles
Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.
research Discovery of New Drug Therapies Based on the Study of Adverse Reactions
Side effects of drugs can lead to the discovery of new treatments.
research Impact of Cernitin on Induced Chronic Prostatitis in Animal Model for Understanding Management of Lower Urinary Tract Symptoms
Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.
research Non-Biologic Immunosuppressive Drugs for Inflammatory and Autoimmune Skin Diseases
Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.
research Time-Tracking-Based Research of Drug Development in Pharmaceutical Fields: A Case Study on Metformin
The conclusion is that metformin may be useful for treating various conditions beyond diabetes and that time-tracking analysis is a good way to review drug research.
research HDL as Therapeutic Tools
Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
research Chemically Induced Hair Loss/Alopecia
Some chemicals and drugs can cause hair loss, which usually grows back after stopping the treatment.
research Evaluation of Caffeine Liberation from Dermal Semisolid Drugs
The optimal concentration for caffeine release in gel form is 0.2% caffeine and 2.3% chitosan.
research Botanical Extracts in Cosmetics and Pharmaceuticals: Historical Use, Regulatory Approaches, and Extraction Processes
Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.
research Liposomal Systems as Drug Delivery Vehicles for Dermal and Transdermal Applications
Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
research Analysis of Hormone Antagonists in Clinical and Municipal Wastewater by Isotopic Dilution Liquid Chromatography Tandem Mass Spectrometry
Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.
research Hair Growth: Focus on Herbal Therapeutic Agents
Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.
research Untargeted Scanning of Hair for Drugs of Abuse by Direct Analysis in Real Time–High-Resolution Mass Spectrometry
A new method can quickly and accurately detect drugs in hair.
research Middle East Medicinal Plants in the Treatment of Diabetes: A Review
Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.
research Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents
Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
research Chapter 17: Selective Androgen Receptor Modulators (SARMs)
Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
research In Vitro Selective Inhibition of Human UDP-Glucuronosyltransferase (UGT) 1A4 by Finasteride and Prediction of In Vivo Drug–Drug Interactions
Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.
research Expression of Type 1 5α-Reductase and Metabolism of Testosterone in Reconstructed Human Epidermis: A New Model for Screening Skin-Targeted Androgen Modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Determination of Illegal Adulteration of Dietary Supplements with Synthetic Hair-Growth Compounds by UPLC and LC-Q-TOF/MS
The new method accurately detects illegal hair-growth drugs in dietary supplements.
research Thyroid Receptor β: A Promising Target for Developing Novel Anti-Androgenetic Alopecia Drugs
Thyroid receptor β can help develop new drugs to treat hair loss.
research Harmonic Vibrational Frequency Simulation of Pharmaceutical Molecules via a Novel Multi-Molecular Fragment Interception Method
The new method provides more accurate vibrational frequencies for drug molecules than traditional models.
research Improving the Efficacy of Anti-Hair Loss Drug Treatments With a Cosmetic Lotion Containing Caffeine, Taurine and Growth Factors
Adding a cosmetic gel with caffeine, taurine, and growth factors to standard hair loss treatments could improve results.
research Court of Appeal Can Overrule Itself to Follow the EPO: UK Adopts EPO Stance on Second Medical Use Claims
The UK Court of Appeal ruled that new dosing regimens for drugs can be patented, aligning with the European Patent Office's approach.