22 citations
,
December 2020 in “mSphere” This study identified a fungal sulfotransferase enzyme, FgSULT1, from *Fusarium graminearum*, expanding the sulfotransferase superfamily and offering new biocatalytic methods for producing bioactive sulfates.
22 citations
,
November 2018 in “Brazilian Journal of Pharmaceutical Sciences” This review discusses iontophoresis, low-frequency ultrasound, and microneedles for enhancing topical drug delivery in dermatological treatments and reports no clinical results; it emphasizes their mechanisms and potential uses.
22 citations
,
July 2004 in “International Journal of Cosmetic Science” This article reviews the impact of UV radiation and visible light on human hair structure and summarizes protective strategies, reporting no new clinical results.
22 citations
,
October 2001 in “Biochemical Pharmacology” This study found that GI198745 acts as a time-dependent inhibitor of rat 5α-reductase type 2 but a rapid-equilibrium inhibitor of type 1, potentially making it more effective than finasteride in preventing rat prostate growth.
22 citations
,
May 2011 in “European Journal of Cancer” This phase I study determined that a combination of oral SU-014813 and docetaxel is a feasible treatment with a manageable safety profile and potential anti-tumor activity, particularly noted in melanoma and GIST patients.
22 citations
,
April 2006 in “Journal of Dermatological Science” This study reports that versican expression plays a crucial role in maintaining the anagen phase and hair inductive properties, as shown in a transgenic mouse model and hair growth assays.
22 citations
,
May 2002 in “Skin Research and Technology” This study found that in male androgenetic alopecia, the contrast enhanced phototrichogram technique was superior in detecting changes in hair density and thickness compared to other methods.
22 citations
,
September 1986 in “Journal of Investigative Dermatology” This study found that low-dose topical alpha-terthienyl combined with UVA radiation can induce cutaneous photosensitization in guinea pigs, suggesting a possible photochemotherapy approach for skin diseases like psoriasis.
21 citations
,
October 2023 in “The Journal of Physical Chemistry C” This study used theoretical calculations to show that phosphates strongly bind to cerium dioxide surfaces in various stable configurations, with spectral signatures identifiable in the infrared and Raman spectra, informing future experimental efforts in controlling the enzymatic activity of ceria nanoparticles.
21 citations
,
January 2012 in “Annals of Dermatology” This study reported that Ell-Cranell® alpha 0.025% solution significantly increased hair counts and diameter in Korean women with female pattern hair loss over an 8-month period, showing both efficacy and safety.
21 citations
,
December 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study demonstrates that T-cell responses in extensive alopecia areata scalp may be aberrantly regulated, with reduced cytokine production but activated phenotype, providing insight into the disease's immune mechanisms.
21 citations
,
January 2003 in “Seminars in reproductive medicine” This review outlines the underlying pathophysiology and treatment options for the androgen excess and reproductive and metabolic manifestations of polycystic ovary syndrome, but reports no clinical results.
21 citations
,
May 2023 in “The Journal of Allergy and Clinical Immunology In Practice”
21 citations
,
January 2019 in “Experimental dermatology” This review explores how low-energy He-Ne laser therapy may stimulate repigmentation in vitiligo by affecting mitochondrial pathways and melanocyte function, but does not report new clinical results.
21 citations
,
April 2018 in “Journal of Dermatological Science” This study found that topical cilostazol promotes hair growth, enhances hair follicle activities, and may serve as a potential treatment for alopecia.
21 citations
,
November 2015 in “Phytomedicine” This study found that glycyrrhizic acid significantly reduced stem cell characteristics of dermal papilla cells by down-regulating key signaling pathways, suggesting potential use in suppressing unwanted hair growth.
21 citations
,
December 2007 in “Journal of Investigative Dermatology” This study proposes the sebogenic hypothesis, suggesting that hair follicles evolved from primitive sebaceous glands to facilitate lipid transport and improve water retention in early land-dwelling animals.
20 citations
,
March 2005 in “Current Medicinal Chemistry” This study reports that newly synthesized steroidal trienones exhibit higher 5α-reductase inhibitory activity than dienones in various biological models, suggesting potential use in treating androgen-dependent diseases.
20 citations
,
September 2022 in “Journal of Biomedical Optics” This article reviews the potential of using PBM in 3D tissue engineering to improve cell viability under stress conditions but reports no new experimental findings.
20 citations
,
December 2021 in “Plants” This review concludes that Tamarix aphylla, used traditionally for ailments such as tuberculosis and hepatitis, demonstrates various pharmacological activities, including antidiabetic and wound-healing effects, but stresses the need for further research to confirm its safety and effectiveness in humans.
20 citations
,
October 2006 in “Skin Research and Technology” This study found that in women with androgenetic alopecia, hair density is lower, and thin and non-growing hair are more common on the midscalp compared to the occiput.
20 citations
,
June 1995 in “Tetrahedron Letters” This study reported that newly synthesized phenanthridin-3-one derivatives effectively inhibit human steroid 5-α-reductase.
19 citations
,
October 2024 in “Molecular Pharmaceutics” This review discusses the challenges of traditional phytochemical delivery methods and highlights the potential of microneedles to improve intra/transdermal delivery, reporting no new clinical results.
19 citations
,
September 2023 in “Journal of Biomedical Science” This review explores how the interaction of AKT and β-catenin signaling pathways, alongside photobiomodulation effects on cellular signaling proteins, could potentially enhance diabetic wound healing by addressing dysregulated cellular signaling.
19 citations
,
August 2019 in “Journal of Cellular Biochemistry” This study found that adipose‐derived stem cells can restore skin barrier function and inhibit photoaging-related responses in UVB-irradiated mice, suggesting a potential therapeutic role in managing skin photoaging.
19 citations
,
February 2016 in “Journal of The American Academy of Dermatology” This study found that the presence of CD3(+) T-cells within empty follicular fibrous tracts is a reliable indicator for diagnosing diffuse alopecia areata instead of pattern hair loss.
19 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article discusses the evolution and variation of hairlines in men and women across different ages, introducing a modeling system to standardize the anatomical description of hairlines, without reporting new experimental findings.
19 citations
,
January 1999 in “Journal of cutaneous laser therapy” This review discusses various hair removal techniques, particularly focusing on laser hair removal, and reports no clinical results; it emphasizes the need for ongoing research to assess effectiveness.
19 citations
,
September 1971 in “Journal of Investigative Dermatology” 18 citations
,
May 2024 in “Pharmaceutics” This review discusses advances in drug delivery systems to enhance oleanolic acid's bioavailability and therapeutic potential but reports no new clinical results.