January 2015 in “Indian Journal of Medical Biochemistry” Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
May 2014 in “Journal of Investigative Dermatology” This article reviews recent imaging and genetic tool advances that enable in vivo study of hair regeneration and assessment of skin parameters, but it reports no new clinical results.
January 2012 in “Methods in pharmacology and toxicology” This review discusses the expanding understanding of TRPV3's role in pain and skin pathology, while highlighting the need for further pharmacological research to fully resolve its functions.
249 citations
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November 2003 in “Clinical endocrinology” This review discusses the complex etiology of polycystic ovary syndrome (PCOS), highlighting its association with insulin resistance and hyperandrogenism, but reports no clinical findings; the authors suggest further investigation of the pathophysiological mechanisms.
31 citations
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November 2016 in “Cell Reports” This study reveals that somatosensory neurons in mouse skin exhibit structural plasticity during hair-follicle regeneration, which may temporarily impair the reliability of encoding gentle touch.
17 citations
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May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” This study found that fasting insulin levels are associated with increased cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.
3 citations
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September 2017 in “Pediatric Dermatology” This article discusses contact dermatitis linked to alopecia and hyperpigmentation, but it reports no new clinical results.
2 citations
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February 2021 in “Brain Research” This study found that testosterone replacement in castrated male rats counteracted endotoxemia-induced arterial baroreflex dysfunction without significantly affecting neuroinflammation.
205 citations
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July 2009 in “Journal of Dermatological Science” This review discusses gender-linked skin differences, such as hormone metabolism and sebum production, and reports no new findings; it suggests these insights might inform male-specific dermatological treatments or cosmetic products.
63 citations
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November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” This study observes the expression of mRNA for androgen receptor, 5α‐reductase, and 17β‐hydroxysteroid dehydrogenase in human dermal papilla cells.
37 citations
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January 2013 in “Postepy Dermatologii I Alergologii” This article discusses isotretinoin for severe acne vulgaris, noting its effectiveness but also highlighting significant side effects on skin, mucous membranes, and hair; it reports no new clinical results.
4 citations
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January 2018 in “Forensic Science International” This study reported that a newly developed UHPLC-MS/MS method detected illegal synthetic hair-growth compounds in 10% of 76 hair-growth products, highlighting the need for ongoing monitoring to protect public health.
115 citations
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November 2004 in “Brain Behavior and Immunity” This study found that stress increases the number of peptidergic nerve fibers and mast cell activity in mouse skin, suggesting a significant neuro-immune interaction under stress.
9 citations
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July 2018 in “Current Pharmaceutical Design” This review discusses the importance of heme oxygenase in skin physiology and disease, but it reports no new clinical results; the authors highlight its potential as a treatment target for conditions like atopic dermatitis and psoriasis.
40 citations
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July 2013 in “Skin Pharmacology and Physiology” This study reports that among men, skin surface hydration and pH change with age, but transepidermal water loss and sebum production show less variation.
19 citations
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February 2016 in “Journal of Biological Chemistry” In this study, researchers observed that knocking out KCNQ3 in mice increased firing frequencies in response to stimuli, particularly at slow mechanical indentation velocities, indicating a role in mechanosensory neuron sensitivity.
3 citations
,
November 2022 in “Frontiers in Oncology” This review discusses the role of melanin synthesis in melanoma, focusing on how melanosomal pH might regulate melanin production, and reports no new results.
This study found that the Arabidopsis cation chloride cotransporter CCC1 is critical for regulating pH in the trans-Golgi network/early endosome, impacting plant growth and stress response.
12 citations
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December 2023 in “Plant Communications” This study found that long-term exposure to high pH extends root hair elongation by altering actin filament arrangements and vesicle trafficking, but disrupting ADF8/11 function shortens root hairs by affecting these processes.
6 citations
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September 2023 in “Experimental physiology” In this study, researchers identified the PLD-mGluR protein in primary mechanosensory terminals as the homomeric GluK2 kainate receptor, functioning purely metabotropically, which is suggested to be common to various sensory endings.
4350 citations
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May 2012 in “Arthritis & Rheumatism” This study found that the new SLICC classification criteria for systemic lupus erythematosus were more sensitive and resulted in fewer misclassifications than the current ACR criteria, although they had lower specificity.
2 citations
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January 1968 in “PubMed” This study found that X-irradiation causes hair dysplasia through two mechanisms influenced by oxygen, and cystamine injections after irradiation enhance this effect.
24 citations
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April 2008 in “Fertility and sterility” In this study, pioglitazone treatment in insulin-resistant PCOS patients decreased relative 5alpha-reductase activity without significantly affecting cortisol levels or urinary cortisol excretion.
March 2008 in “British Journal of Pharmacology” This guide provides an overview of the complex roles and mechanisms of various receptors and channels in pharmacology but does not report new experimental results.
January 2026 in “Regenerative Biomaterials” This study highlights that hydrogel formulations unexpectedly prolonged healing in trials, pointing to a need for design based on detailed pathophysiological insights rather than empirical methods, and suggests technologies like AI materials optimization and 3D bioprinting to aid their clinical use for cancer survivors.
1 citations
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August 2023 in “Military Medical Research” This review discusses recent advancements in responsive-hydrogel dressings for diabetic wound healing, highlighting their design, responsiveness, and degradation behavior, and evaluating their potential advantages and limitations in clinical applications.
188 citations
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June 1998 in “Molecular cell” This study found that mimicking the XPD point mutation in mice resulted in trichothiodystrophy-like symptoms, supporting the role of basal transcription and DNA repair defects in the disease.
63 citations
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May 2009 in “Dermato-endocrinology” This review explores the role of FGFR2b-signaling in the pathogenesis of acne, highlighting its influence on sebaceous gland physiology and the effects of anti-acne agents like isotretinoin.
3 citations
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August 2020 in “Nutrition Journal” This study found that spinach-derived thylakoid supplementation, combined with a calorie-restricted diet, led to more significant improvements in weight loss and insulin sensitivity in obese women with PCOS than calorie restriction alone.
November 2025 in “Biomedicines” This review highlights hypochlorous acid's potential benefits in various medical fields due to its antimicrobial and healing properties but stresses the need for further research on dosing and product development.