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Martin-Perez et al. show that rapamycin's beneficial effects in a mouse model of Leigh syndrome are linked to the downregulation of protein kinase C.

This study found that Cacumen platycladi extract significantly promoted hair growth and reduced dihydrotestosterone levels by inhibiting 5α-reductase activity in an androgen-sensitive mouse model.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

In this study, the use of two emollients significantly reduced itching severity in individuals with xerotic eczema, starting 30 minutes post-application, and improved skin moisture and lipid content over 14 days, while demonstrating good tolerance with few adverse events.

This review highlights the eye and skin manifestations of endocrine-related metabolic diseases but provides no new clinical results.

This study found that the ethyl acetate fraction of Hibiscus rosa sinensis petals significantly reduced serum glucose and glycated hemoglobin levels in diabetic rats, showing effects comparable to the standard drug metformin.

This animal study found that second generation mice exposed to excess zinc during gestation and lactation had reduced plasma copper, body weight, and hematocrit, with lighter and delayed hair development compared to mice on a normal zinc diet.

This study found that male pattern baldness may serve as a clinical marker for circulating sex hormone levels in men with localized prostate cancer, while chest hair density showed no significant hormone association.

This review highlights that current in vitro models often fail to replicate the physiological oxygen levels experienced by different skin cell types, which could affect redox states and functions, potentially accelerating skin aging.

Lower GATA3 levels in mice help hair regrow by changing certain immune cells.

In this study, PFOS exposure altered steroid hormone levels and enzyme activities related to steroidogenesis in juvenile Silurana tropicalis, with effects differing between male and female frogs.

This review discusses the skin manifestations of endocrine diseases and reports no new clinical findings, emphasizing the importance of recognizing these signs for early diagnosis.

This study observed that extracellular ATP (eATP) levels outside Arabidopsis root cells vary inversely with the expression of AtAPY1 and AtAPY2 apyrases, suggesting these enzymes regulate eATP concentrations crucial for root growth.

In this randomized study, BAY 1158061, a prolactin receptor antibody, was found to be safe, well-tolerated, and exhibited low immunogenicity in healthy postmenopausal women, but had no effect on serum prolactin levels compared to placebo.

This article discusses the role of filaggrin gene mutations in understanding atopic dermatitis and their link to allergic sensitization but does not report new clinical results.

In this study, researchers found that the efflux of calcium in root hairs of Arabidopsis thaliana, particularly through the ER-localized ACA2 and ACA7, is crucial for modulating cytoplasmic calcium signals and enabling proper root hair growth, with disruptions leading to impaired elongation.

This study found that metformin treatment significantly decreased gremlin levels and improved insulin resistance in patients with polycystic ovary syndrome.

This study found that pregnant women in Al Muthanna Province, Iraq, frequently have low serum zinc and ferritin levels, especially those experiencing hair loss, posing a significant public health concern.

This case report documents a cat with necrolytic migratory erythema due to glucagonoma and diabetes mellitus, highlighting similarities to glucagonoma syndrome in humans.

This study described four adult male cases of Kennedy disease with typical neurological symptoms and noted gynecomastia as the most frequent endocrinological manifestation, accompanied by an abnormal expansion in the androgen receptor gene.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Environmental, chemical, mechanical, and personal health factors can all damage hair and contribute to hair loss or changes in hair quality.

This study found that zinc levels in hospitalized patients with significant weight loss did not correlate with taste perception or vitamin A status, even in those with reduced taste acuity.

This study provides evidence that psychoemotional stress inhibits hair growth in mice by affecting the brain-hair follicle axis, with specific neuropeptides and treatments modulating this effect.

This study found that stress increases the number of peptidergic nerve fibers and mast cell activity in mouse skin, suggesting a significant neuro-immune interaction under stress.

This review summarizes various treatment options for polycystic ovary syndrome, noting that while some treatments address specific symptoms, no single therapy fully resolves the condition.

This review discusses the importance of heme oxygenase in skin physiology and disease, but it reports no new clinical results; the authors highlight its potential as a treatment target for conditions like atopic dermatitis and psoriasis.

This study found that hair steroid analysis effectively detected increased hormone levels from both a single testosterone dose and laboratory-induced stress, revealing individual context factors like relationship status also impact hair hormone concentrations.

This study found that intravaginal testosterone significantly improved sexual satisfaction and reduced dyspareunia in postmenopausal women using aromatase inhibitors, with no effect on urinary incontinence.

This study found that patients with alopecia areata had significantly lower Vitamin D levels compared to controls, with a negative correlation between Vitamin D levels and disease severity.