Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that compounds 21–23 and 25 exhibited strong 5α-reductase II inhibition in vitro and significantly reduced rat prostate weight, performing comparably to finasteride.

This study found that a synthetic avicequinone C analogue, 5e, was significantly more potent in inhibiting steroid 5α-reductase type 1 activity in human keratinocytes compared to the original isolated compound.

This study reported that newly synthesized progesterone derivatives significantly reduced prostate weight in testosterone-treated hamsters, with 5alpha-reductase inhibitory activity dependent on the size of the substituent at C-17.

In this study, 4-substituted N-(1,1-dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides were synthesized and evaluated in vitro as potential 5 alpha-reductase inhibitors and antiandrogens.

This review examines the methods and challenges in androgen laboratory diagnostics, discussing their advantages, limitations, and evolution; it presents no new experimental results.

In this study, a square pulse, low-fluence IPL device used at home significantly reduced terminal hair count by 87% six months post-treatment, with evidence of hair miniaturization similar to professional laser treatments.

This study found that finasteride gel 0.25% significantly decreased hair growth in women with idiopathic hirsutism over six months without any reported side effects.

In this study, elevated prolactin and DHEA-S levels along with reduced SBP were observed in fertile non-obese women with moderate body hair compared to controls, and ethynylestradiol plus desogestrel or cyproterone acetate treatment improved clinical outcomes by increasing SBP.

This study formulated and evaluated a herbal shampoo with natural ingredients, finding it to be a viable alternative for hair cleansing and maintenance without adverse effects, suggesting it could reduce reliance on shampoos with synthetic chemicals.

This article reviews the potential health benefits of onions, highlighting their anti-inflammatory, anticancer, and antioxidant properties, but does not report any new clinical results.

In this experimental study, researchers developed and optimized metformin-loaded mucoadhesive microspheres for sustained anti-hyperglycemic and anticancer activity, demonstrating high entrapment efficiency, enhanced α-amylase and α-glucosidase inhibition, improved cytotoxicity against breast cancer cells, and promising stability.

This preclinical study found that Mesenchymal Stem Cell-derived Conditioned Media formulations were safe and effective in rat and mouse models for treating chemotherapy- and radiation-induced oral mucositis, demonstrating improved tissue regeneration and healing, most notably at higher concentrations.

This study aimed to develop a natural hair serum using ingredients like myroxylon balsam oil, flaxseed, almond oil, and Vitamin E, which are noted for benefits such as reducing dandruff, enhancing shine, calming the scalp, and promoting hair growth.

In this study, researchers developed a herbal hair dye using henna and other natural ingredients that achieved a color similar to natural black on blonde hair, though further testing on various hair shades is needed to explore its full benefits.

In this study, researchers examined a patient with ZMYM2::FGFR1 fusion-positive leukemia, finding that Pemigatinib showed efficacy, while Ponatinib resistance was linked to a specific FGFR1 mutation. Other FGFR inhibitors demonstrated high effectiveness in ex vivo assays.

This study reviews the use and benefits of herbal cosmetics in addressing common hair issues like baldness, hair fall, and dandruff, highlighting that herbal products may offer fewer side effects than conventional beauty products.

This study reviews the importance of herbal cosmetics in addressing common hair problems like dandruff and hair fall, emphasizing the potential benefits of herbal hair formulations that provide essential nutrients with fewer side effects compared to conventional beauty products.

This study reported that a solid lipid nanoparticle-based gel formulation, specifically optimized for psoriasis, improved drug loading capacity and release properties using high-pressure homogenization, suggesting its potential efficacy as a topical treatment.

This study found that ethanolic and petroleum ether extracts of Cuscuta reflexa, as well as an isolate from these extracts, improved hair growth and follicle characteristics in androgen-induced alopecia in rats.

This study reported that newly synthesized nonsteroidal compounds were effective at inhibiting prostatic 5 alpha reductase isozyme 2, especially the compound with an N, N-diisopropylcarbamoyl substituent, suggesting potential for treating benign prostatic hyperplasia.

This study found that in male rats, hesperidin co-administration ameliorated finasteride-induced testicular toxicity by reducing oxidative stress and improving antioxidant status, sperm parameters, and enzyme activity compared to finasteride treatment alone.

This study aimed to create an herbal shampoo that effectively removes oil, dirt, and dandruff while enhancing hair thickness, growth, and blackness, without causing side effects like conventional cosmetic shampoos can. Results are not reported.

This review examines the design and evaluation parameters of depilatory formulations but reports no new empirical findings.

This study developed a topical dutasteride-loaded Insitu-emulgel for treating androgenetic alopecia, finding it effectively controls drug release, enhances skin penetration, and may improve patient compliance compared to traditional topical treatments, though further clinical research is underway.

In this study conducted at Saveetha Dental College, researchers found that the severity of male androgenetic alopecia, as graded by Norwood's classification, increased with age, although other factors such as genetic or hormonal influences were not assessed.

This study explored the development of herbal hair gels using natural extracts like flaxseed and guava leaves, targeting the reduction of dandruff and regulation of hair loss through antimicrobial and anti-inflammatory properties, though specific results of efficacy are not reported.

The study developed herbal shampoo formulations using isolated phytoconstituents, such as eugenol, rutin, menthol, and camphor, which demonstrated similar antifungal efficacy to ketoconazole but with improved safety and detergency, offering a promising alternative for managing seborrheic dermatitis.

This study found that nanoparticles did not permeate intact rat skin but could penetrate skin that had been artificially punctured, primarily through grooves or hair follicles.

This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.

This study reported that sunscreen with SPF50+ provides a high level of DNA protection against UV-induced damage in a reconstituted human epidermis model, comparable to that in skin explants.