21 citations
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July 2002 in “Clinical and Experimental Dermatology” This article discusses the role of cosmetic hair care products in hair loss and concludes they do not cause it, suggesting a need for clinicians to understand the hair cycle and cosmetic practices for accurate diagnosis.
10 citations
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May 2018 in “Cell death discovery” This study found that the interaction between heat shock protein 90 and lamin A/C is crucial for the growth, migration, and self-aggregation of dermal papilla cells, suggesting a potential role in alopecia areata mechanisms.
4 citations
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March 2018 in “PloS one” This study found that among men over 70, certain genetic variants associated with skin pigmentation affect serum PSA levels, with implications for how sun sensitivity and exposure may influence prostate cancer risk.
3 citations
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October 2022 in “PloS one” This study developed a method to culture and maintain chicken feather follicles in vitro, preserving structure and biology similar to their in vivo state, though some gene expression was altered.
2 citations
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March 2005 in “Cancer biology & therapy” This study found that 95% of untreated advanced-stage follicular lymphoma patients responded to a single course of the Bexxar regimen, with 75% achieving complete remission and remaining disease-free for years.
This research explores the use of serial block-face scanning electron microscopy to model the complex architecture of sheep wool fibres, focusing on the role and distribution of para- and ortho-cortical cells in determining wool curliness, though the mechanism remains unclear.
In this study conducted at Saveetha Dental College, researchers found that the severity of male androgenetic alopecia, as graded by Norwood's classification, increased with age, although other factors such as genetic or hormonal influences were not assessed.
May 2022 in “Gastroenterology” This study investigated the possible role of neutrophil extracellular traps in contributing to fibrosis in stenotic Crohn's disease.
215 citations
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March 2011 in “Clinical Cancer Research” This study found that sorafenib was active against desmoid tumors, with 25% of patients achieving a partial response and 70% maintaining stable disease.
100 citations
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November 2021 in “Cell Research” This study found that SARS-CoV-2 hijacks the host factor IGF2BP1 to stabilize its RNA and enhance translation, and identified Cepharanthine and Trifluoperazine as potential treatments against the virus.
50 citations
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July 2021 in “Nature Communications” This study found that the antiandrogen drug enzalutamide reduced TMPRSS2 levels and significantly decreased SARS-CoV-2 entry and infection in lung cells, supporting further clinical trials for COVID-19 treatment.
25 citations
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July 2019 in “Journal of drug delivery science and technology” This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.
20 citations
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October 2021 in “PLoS ONE” This study found significant differences in gene expression between newborn and adult skin, with infant skin notably increasing processes related to ECM organization, cell adhesion, and collagen fibril organization.
18 citations
,
September 2018 in “Experimental physiology” This study observed that electro-acupuncture reduced global DNA methylation and DNMT3b expression in a PCOS-like rat model, suggesting a role of hypothalamic DNA methylation in PCOS development and treatment.
11 citations
,
August 2020 in “Diabetes” This study found that testosterone enhances insulin secretion in human pancreatic islets by being converted into DHT and E2, processes that are necessary for this effect.
11 citations
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September 2020 in “Journal of Cosmetic Dermatology” This study found that Blumea eriantha silver nanoparticles promoted hair growth in treated animals, with activity comparable to minoxidil in terms of anagen follicle transition.
11 citations
,
February 2019 in “Frontiers in Physiology” This review explores the complex interrelationships among different properties of natural hair fibers and underscores the need for a holistic taxonomy to improve data interpretation across disciplines, but it reports no new experimental results.
9 citations
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August 2019 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil activation by hair enzymes predicts treatment success for female hair loss.
8 citations
,
July 2024 in “PLoS ONE” In a comparative genomic study, researchers observed significant genetic differences among the three chemical races of the alga Botryococcus braunii, leading them to propose reclassifying these races as distinct species based on their unique genomic characteristics.
8 citations
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February 2014 in “General and Comparative Endocrinology” In this study, exposure to the drug finasteride in Silurana tropicalis significantly increased testosterone levels in liver and testis tissues and altered gene expression related to male reproduction and oxidative stress.
7 citations
,
June 2024 in “Communications Medicine” In this study, researchers analyzed spaceflight data from various sources and found that skin issues during spaceflight are linked to DNA damage, mitochondrial dysregulation, and gene alterations, while also highlighting the skin's adaptability post-flight.
7 citations
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March 2025 in “Archives of Dermatological Research” This study found that trichoscopy is essential for evaluating the severity of alopecia areata and predicting treatment responses, contributing to more personalized patient management.
5 citations
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April 2018 in “Journal of Dermatological Science” This study found that the E2-ANGPT2 pathway is involved in hair follicle regulation and that ANGPT2 treatment increased hair density in modeled female pattern hair loss, suggesting potential therapeutic use.
4 citations
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July 2025 in “Molecular Diversity” This review outlines drug repurposing as an efficient, low-cost strategy to identify new uses for existing drugs, highlighting various computational and experimental approaches as well as publicly available databases to aid in personalized pharmacotherapy.
3 citations
,
September 2019 in “Clinical and experimental dermatology” This study found that basal cell carcinoma cells differentiate along hair follicle lineages and may be influenced by hair follicle cycle modulators for potential therapeutic targeting.
2 citations
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December 2025 in “Nature Communications” This study found that the repressive histone mark H2AK119ub links inhibitory FGF signals with the quiescent state in hair follicle stem cells, revealing a signaling-epigenetic axis crucial for maintaining stem cell quiescence and tissue homeostasis.
2 citations
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March 2016 in “The Journal of Dermatology” The researchers reported that the facial Psoriasis Log-based Area and Severity Index (fPLASI) more reliably and sensitively captured clinical improvement in facial psoriasis than the existing facial Psoriasis Area and Severity Index (fPASI).
This study introduced Cadd4, a peptide-based degrader developed using computer-aided drug design, which effectively reduced PCSK9 levels and increased LDL receptor expression, resulting in decreased plasma cholesterol and LDL-C levels in hypercholesterolemic mice, without liver toxicity.
1 citations
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September 2025 in “PLoS ONE” This study identified numerous drugs with potential to trigger vitiligo, cautioning that these pharmacovigilance findings need further validation and that patients on these medications should be monitored for vitiligo development.
1 citations
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January 2025 in “medRxiv” In this case-control study, researchers did not find genome-wide significant genetic variants for trichotillomania, but cases had higher polygenic risk for psychiatric disorders and certain neuropsychiatric-associated copy number variants.