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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Higher miR-34a levels and the A variant of the MIR-34A gene are linked to increased risk and severity of alopecia areata.

Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.

PRP may help with aging and osteoarthritis, improving tissue repair and reducing surgery risk.

New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

Metabolites and diet affect hair growth cycles in cashmere goats.

Bimatoprost helps with hair growth and eye conditions but can be costly and have side effects.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

After skin is damaged, noncoding dsRNA helps prostaglandins and Wnts work together to repair tissue and promote hair growth.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Astrotactin2 affects hair follicle orientation and skin cell polarity.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The new formulation improved the skin absorption of the drug Thiocolchicoside.