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This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.

This study suggests that the hydrogel nanoparticle formulation of hair growth-promoting compounds may enhance hair follicle penetration and induce hair growth in tested models, demonstrating its potential as a hair growth treatment.

This study found that collagen sponges with polyglycolic acid fibers support proper skin and hair follicle restructuring, suggesting potential usefulness for hair reconstitution research and clinical applications.

This study found that using engineered skin with PGA-collagen scaffolds, combined with hair follicle stem cells and other cell types, effectively repaired full-thickness skin defects in nude mice.

This study systematically reviews the development and applications of drug-loaded nanofiber scaffolds in wound healing, highlighting challenges such as maintaining drug activity and achieving controlled release, while summarizing preparation methods and describing advanced drug delivery schemes.

In this study, topical finasteride 0.25% showed sustained effectiveness over 52 weeks, especially in the frontotemporal areas of men with androgenetic alopecia, while maintaining an excellent safety profile.

In this study, microneedle-assisted delivery of polyglutamate significantly improved hair parameters, scalp symptoms, and quality of life in androgenetic alopecia patients, with no serious adverse reactions reported.

This study found that high-dose UVA-1 therapy appeared to improve both patient-reported outcomes and objective clinical measures in patients with morphea and systemic sclerosis, supporting its potential efficacy for treating scleroderma.

This article explores the potential applications of polyglutamic acid in cosmetics, discussing its benefits for skincare and haircare, but reports no new experimental results.

In this randomized controlled trial, the topical application of a PGA solution significantly increased hair density in patients with androgenetic alopecia compared to placebo, with no adverse reactions reported over 24 weeks, suggesting its potential as a safe and effective treatment option.

This study found that the clinical severity of hidradenitis suppurativa, evaluated through Hurley staging, VAS, PGA, and SAHS, significantly affects patients' work absenteeism and presenteeism, with presenteeism being more prevalent.

In this study, oral and topical tranexamic acid significantly improved melasma symptoms in 28 female patients, with all showing over 25% improvement and 50% achieving good improvement, while 92.86% experienced no side effects, suggesting it is an effective and safe treatment.

This study observed that treatment with spironolactone significantly improved pain, inflammatory lesion count, and HS-PGA scores among female patients with hidradenitis suppurativa, suggesting its potential as an effective treatment option, even at lower doses, despite no change in Hurley stage or fistula count.

This study found that ultra-high molecular weight poly-γ-glutamic acid promoted hair growth in telogenic C57BL/6 mice by inhibiting 5-alpha reductase activity and inducing the anagen phase.

In this clinical trial, patients with lichen planopilaris treated with the oral TYK2 inhibitor deucravacitinib showed significant improvement in PGA, LPPAI, and Skindex-16 scores over 24 weeks, with transcriptomic analyses indicating decreased inflammatory and immune pathway activity post-treatment.

In this animal study, researchers found that daily oral intake of salmon nasal cartilage proteoglycan enhanced hair growth in mice, potentially through a signaling pathway that stimulates specific growth factors in human follicle cells.

This study identified TGFβ-2 as a potential driver of progenitor cell loss in hair follicles from early androgenetic alopecia scalps, suggesting its role in the condition's molecular disturbances.

This study concluded that oral tofacitinib significantly improved symptoms in patients with lichen planus pigmentosus who did not respond to conventional treatments, showing it as a viable alternative.

This study concluded that Glycolon is the preferred suture material for tooth extraction surgery due to its superior mechanical properties and capillarity compared to other materials.

This study found that in patients with frontal fibrosing alopecia, combining topical tacrolimus with isotretinoin is more effective after four weeks of treatment compared to tacrolimus with finasteride, though both regimens offered some benefit.

This study observed that gold thread implantation increased hair regrowth in both human patients and mice, suggesting it could be an effective hair regrowth treatment, although further studies are needed to understand its mechanisms and safety.

This study identified a shared gene signature in scarring alopecia subtypes, with increased mast cell presence, suggesting similar treatment approaches may be effective across these hair loss disorders.

In this study, researchers used Raman spectroscopy to identify melanin-specific features in mouse hair as potential biomarkers for gamma-radiation exposure, achieving a sensitivity of 88% and specificity of 83%, with classification accuracy declining over time beyond 7 days post-irradiation.

In laboratory experiments, this study found that the topical prodrug SCD-153, a derivative of 4-methyl itaconate, reduced inflammation-related gene expression and induced significant hair growth in mice, suggesting it as a promising treatment candidate for alopecia areata.

This study integrated single-cell RNA-seq data from four previous studies to create a comprehensive human corneal cell state meta-atlas, revealing novel marker genes, rare cell states, and distinct transcription factors, and offering a tool to enhance future cornea research.

This review assessed patient-reported outcome measures for alopecia treatments but found that none met current FDA guidelines; however, some could potentially be adapted for more comprehensive use.

This study describes a simple, noninvasive hair counting method used in a hair growth prevention trial, assessing its reliability and validity.

This review discusses the development and future prospects of biomaterials for in situ tissue regeneration but reports no new research results; it underscores the importance of biomaterials in addressing tissue defects.

This study reports that oral spironolactone may be a useful and low-cost first-line treatment for hidradenitis suppurativa in women, with relatively few side effects.

This study observed enduring sexual dysfunction reported in 300 cases globally following the use of SSRIs, finasteride, and isotretinoin, with common symptoms like genital anaesthesia and loss of libido.