61 citations
,
October 1996 in “Development” This study found that combining adult germinative epidermal cells with non-inductive dermal cells can stimulate hair follicle neogenesis, effectively altering the cells' status to enhance induction.
17 citations
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August 2020 in “Stem Cell Research & Therapy” This study found that a 3D co-culture of endothelial colony-forming cells and adipose-derived stem cells restored stem cell properties and improved healing in a mouse model of chronic injury.
1 citations
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January 2021 in “SISTEMASI” This study found that the multi-thresholding method was the most effective for segmenting hair during laser removal, as it clearly distinguished hair patterns with minimal noise.
19 citations
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July 2017 in “PLoS ONE” This study suggests that passage number significantly affects in silico scratch assay results, highlighting the importance of reporting passage number for reproducibility in cell culture experiments.
5 citations
,
December 2017 in “The Journal of Dermatology” This report describes a unique case of Schöpf–Schulz–Passarge syndrome in a Taiwanese man linked to a previously unreported homozygous WNT 10A mutation, underscoring its role in ectodermal dysplasia.
46 citations
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September 2014 in “Tissue engineering. Part A” This study found that a 3D Matrigel culture technique for dermal papilla cell spheroids can enhance hair follicle inductivity and induce hair-like fiber differentiation in vitro, even with high-passage cells.
January 2026 in “Non-coding RNA Research” This study found that low-passage exosomes from dermal papilla cells enhance hair follicle stem cell proliferation and that miR-218-5p may serve as a potential biomarker and therapeutic target for hair growth.
October 2022 in “Amplla Editora eBooks”
62 citations
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February 2016 in “ACS Applied Materials & Interfaces” This study found that 3D microtissue models of dermal papilla cells can enhance the ability to induce hair-follicle neogenesis in vivo, offering potential for controlled cell production in follicle regeneration.
19 citations
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December 2016 in “PLOS ONE” This study found that proteins secreted by early-passage dermal papilla cells, including SDF1, MMP3, biglycan, and LTBP1, may play significant roles in hair follicle regeneration.
7 citations
,
July 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” This study's in silico experiments suggest that the average cell proliferation rate can vary with passage number, highlighting the importance of reporting passage numbers for reproducibility in cell culture studies.
1 citations
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September 2025 in “Cureus” In this study, the ChatGPT-5 model accurately answered 76.47% of questions on the Polish endocrinology specialty exam, surpassing the 60% passing threshold, yet its role in clinical decision-making remains uncertain, highlighting the need for further research.
25 citations
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January 2012 in “Proteome Science” This study suggests that common proteomic changes, including the expression of the protein S100A6, may occur during the expansion of AD-MSC from different donors.
July 2020 in “Research Square (Research Square)” This study found that a 3D co-culture of adipose-derived stem cells and endothelial colony forming cells restored stem cell properties and enhanced wound healing in a mouse model.
October 2025 in “Environment International” This study reports that prenatal and prepubertal exposure to organochlorine compounds and perfluoroalkyl substances may affect pubertal development at age 12, with observed changes in development patterns in both girls and boys, highlighting the need for further research.
4 citations
,
September 2024 in “Jurnal Pengolahan Hasil Perikanan Indonesia” In this study, researchers reported that compounds from Bruguiera gymnorhiza leaves showed anti-inflammatory potential in in silico analyses, with favorable drug properties and specific binding to the IKKβ receptor, suggesting possible development into anti-inflammatory drugs.
3 citations
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March 2022 in “Research journal of pharmacy and technology” This study found that the compound (+)–Marmesin from Petroselinum crispum showed potential as an anti-alopecia agent by demonstrating better binding to androgen receptors than minoxidil, though not surpassing native ligands.
3 citations
,
January 2018 in “Methods in molecular biology” This paper describes a protocol for isolating and culturing skin-derived precursors to potentially induce hair growth and regenerate hair follicles, but reports no new experimental findings.
72 citations
,
September 1975 in “Biology of Reproduction” This study found that zinc is primarily located in the tails of mature rat sperm, associated with -S-S-bonded structures, and suggests a possible similarity in zinc interactions between sperm keratin and hair proteins.
11 citations
,
January 2020 in “Micro and Nanosystems” This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.
9 citations
,
January 2018 in “Hair transplant forum international” This correspondence discusses issues related to overharvesting and challenges in measuring factors that impact donor coverage in hair transplantation procedures, but it does not report specific study results or outcomes.
3 citations
,
January 2019 in “Česká a slovenská farmacie” This review discusses various types of microneedles and their potential to expand the range of drugs delivered via the skin, but reports no new clinical results.
1 citations
,
March 2009 in “Hair transplant forum international” This article discusses patient-driven innovations in hair restoration surgery, including the rise and fall of synthetic fiber implantation, but reports no new clinical findings.
1 citations
,
March 1997 in “Journal of Chromatography B: Biomedical Sciences and Applications” This study discovered that the disposition of LY191704 enantiomers in rats and dogs is both stereoselective and species specific.
January 2026 in “Frontiers in Pharmacology” This review reports that topical minoxidil remains the primary treatment for androgenetic alopecia, while oral and sublingual forms offer alternative options, each with varying efficacy and side effects.
July 2025 in “Future Journal of Pharmaceuticals and Health Sciences” This study developed a polyherbal chocolate formulation aimed at managing PCOS and hormonal balance, finding that formulation F2 showed excellent organoleptic properties and stability, with future in vivo studies being suggested.
This study found that a hair follicle-like structure forms in nude mice when hair papilla cells are mixed with hair follicle epithelium and implanted, but not with dermal sheath cells or fibroblasts.
197 citations
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June 2009 in “American journal of human genetics” This study found that previously undescribed WNT10A mutations are a prominent cause of various forms of ectodermal dysplasia, including OODD and Schöpf-Schulz-Passarge syndrome, with gender-specific phenotypic effects noted.
6 citations
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January 2025 in “Differentiation” This review highlights the role of the glycoprotein WNT10A in human tissue and organ development, exploring its genetic structure, expression, and association with disorders like ectodermal dysplasia and pathological conditions such as fibrosis and cancer.
2 citations
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January 2013 in “Elsevier eBooks” The document explains the genetic causes and characteristics of inherited hair disorders.