11 citations
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December 2011 in “Revista Brasileira de Farmacognosia” In this animal study, petroleum ether and ethanolic extracts of Abrus precatorius seeds appeared to reverse androgen-induced alopecia in male albino rats by inhibiting the 5α-reductase enzyme, similar to finasteride.
7 citations
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September 2014 in “Beni-Suef University Journal of Basic and Applied Sciences” This study found that ethanolic and petroleum ether extracts of Cuscuta reflexa, as well as an isolate from these extracts, improved hair growth and follicle characteristics in androgen-induced alopecia in rats.
7 citations
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February 2013 in “Tropical Journal of Pharmaceutical Research” In this study, applying G. glabra root extract to female rats resulted in faster and more extensive hair growth than minoxidil or a control treatment.
1 citations
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March 2019 in “Journal of Drug Delivery and Therapeutics” This study found that petroleum ether extract of Abrus precatorius leaves at 300 mg/kg promoted hair growth in animal models similarly to 2% minoxidil.
1 citations
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August 2013 in “Asian Journal of Pharmaceutical and Clinical Research” This study found that petroleum ether extract of Glycyrrhiza glabra prevented alopecia in testosterone-treated male rats, demonstrating effects comparable to the standard treatment finasteride.
June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study evaluated petroleum jelly-based bioactive glass ointments with varying copper concentrations for wound healing in chronic wound models, finding that the 3 wt% copper formulation significantly improved healing by enhancing tissue regeneration, vascularization, and antibacterial protection compared to controls.
May 2019 in “Journal of Drug Delivery and Therapeutics” In this study, a petroleum ether extract of Hemidesmus indicus seeds demonstrated hair growth-promoting effects in animal models, comparable to 2% minoxidil, by increasing the transition of hair follicles from telogen to anagen phase.
November 2012 in “International Journal of Data Science and Artificial Intelligence” This study found that the petroleum ether extract of Glycyrrhiza glabra roots promoted faster and longer hair growth in female Wistar rats compared to minoxidil and control treatments.
1 citations
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August 2023 in “Journal of Cutaneous Medicine and Surgery” This study demonstrated that topical anthralin at concentrations of 0.1% to 1% is effective and well-tolerated for treating pediatric alopecia areata, with 0.2% offering the best results and requiring at least six months of treatment to achieve substantial hair regrowth.
January 2025 in “International Journal of Mosquito Research” In this study, the combination of petroleum ether extracts from Jacquinia ruscifolia flowers and Thuja orientalis strobili demonstrated synergistic larvicidal effects against third-instar Culex quinquefasciatus larvae, achieving 100% mortality at 250 ppm with noted synergism particularly in a 1:2 ratio.
96 citations
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January 1940 in “Journal of Endocrinology” This study on rats found that adrenalectomy was associated with increased hair loss compared to sham adrenalectomy, where one adrenal was left intact.
33 citations
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May 2013 in “Andrologia” This study identified several herbs, including Ganoderma lucidum and Urtica dioica, that showed promising 5α-reductase inhibitory activity suggesting potential use in managing androgenic disorders.
31 citations
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September 2009 in “Natural Product Research” In this study, petroleum ether extract of Citrullus colocynthis fruit effectively promoted hair growth in a mouse model of androgen-induced alopecia, showing comparable results to the standard treatment, finasteride.
24 citations
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December 2014 in “International Journal of Molecular Medicine” In this study, researchers found that petroleum ether extract of Eclipta alba significantly stimulated follicular keratinocyte proliferation and reduced TGF-β1 expression in nude mice, suggesting potential use for certain types of alopecia.
24 citations
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June 2011 in “Andrologia” This study found that Ganoderma lucidum extracts reduced prostate enlargement and improved symptoms in testosterone-treated rats, suggesting potential benefits for managing benign prostatic hyperplasia.
21 citations
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November 2021 in “Biomolecules” This review compiles information on traditional uses, phytoconstituents, and biological activities of Eclipta prostrata but reports no new experimental results; the authors call for more studies to understand its pharmacological mechanisms.
19 citations
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January 2010 in “International Journal of Ayurveda Research” In this study, topical application of Tectona grandis seed extracts on albino mice significantly accelerated hair growth initiation time and increased the percentage of hair follicles in the anagenic phase compared to the standard minoxidil treatment.
18 citations
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January 2007 in “Pharmaceutical Biology” This study found that petroleum ether extracts of Citrullus colocynthis reduced hair growth initiation time and advanced more hair follicles to the anagen phase in albino rats compared to untreated controls and minoxidil.
16 citations
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July 2020 in “Advances in Traditional Medicine” This study found that the combined ethanolic extract ethosome formulation of Phyllanthus niruri, Zingiber officianale, and Croton tiglium Linné showed better safety and less cytotoxicity for hair growth promotion compared to the petroleum ether formulations.
14 citations
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July 2017 in “Pakistan Journal of Zoology” Fenugreek leaf extracts significantly promoted hair growth in mice with alopecia.
9 citations
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January 1992 in “Contact Dermatitis” Some people using minoxidil for hair loss developed an allergic skin reaction, often related to an ingredient that helps minoxidil work better.
9 citations
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January 2014 in “DARU Journal of Pharmaceutical Sciences” This study found that Cuscuta reflexa extracts promoted hair regrowth and follicular proliferation in cyclophosphamide-induced hair loss in male rats.
8 citations
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December 2015 in “PubMed” In this study, petroleum ether extracts of Phyllanthus niruri promoted hair regrowth in testosterone-induced alopecia in rats by inhibiting the 5α-reductase enzyme.
5 citations
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January 2007 This study found that topical application of Citrullus colocynthis extracts reduced hair growth initiation and completion times in albino rats and resulted in similar hair follicle anagen phase activation as minoxidil.
3 citations
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June 2010 in “Pharmacognosy journal” This study found that a formulated polyherbal antidandruff hair oil containing eucalyptus and ocimum volatile oils, along with hibiscus and phyllanthus extracts, showed both antifungal and hair growth activities in open pilot clinical trials.
1 citations
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March 2024 in “International Journal of Pharmaceutical Sciences and Drug Research” In this study on albino mice, Helianthus annuus and Martynia annua seed oil extracts in petroleum ether significantly promoted hair growth in a dosage-dependent manner, with 30 mg/ml showing notable results compared to 2% minoxidil.
1 citations
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January 2020 in “Indo global journal of pharmaceutical sciences” This article reviews the traditional uses of Citrullus colocynthis for various conditions like cancer and jaundice but reports no new clinical results, underscoring its role in folk medicine.
1 citations
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January 2017 in “Pharmaceutica Analytica Acta” This study found petroleum ether to be more effective than methanol at extracting β-sitosterol from Eclipta alba, with higher concentrations detected using HPTLC and HPLC methods. The extracted materials contained metals within safety limits.
September 2015 in “Pediatrics in review” This case study reports that a 7-month-old boy's diffuse rash and hair loss were attributed to zinc deficiency and resolved with zinc supplementation.
September 2015 in “Pediatrics in review” The 7-month-old boy has a persistent rash that doesn't improve with typical skin treatments.