11 citations
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October 2015 in “Journal of Cosmetic Dermatology” This study found that musculoskeletal symptoms such as pain and fatigue among hair restoration surgeons were more common and lasted longer after performing follicular unit extraction compared to strip excision procedures.
61 citations
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April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” This study reports that men with androgenic alopecia experience altered neuroactive steroid levels associated with persistent depression symptoms even after stopping finasteride treatment.
March 2026 in “American Journal of Clinical Dermatology” This narrative review provides an overview of the persistent dermatological side effects experienced by cancer survivors due to treatments, highlighting their impact on quality of life and the need for structured dermatological care during survivorship.
December 2025 in “Cureus” This study found that post-COVID syndrome symptoms persisted and were more common in individuals who had recovered from COVID-19 compared to uninfected controls in Kerala, though both groups showed significant symptom burdens.
1250 citations
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August 2021 in “Scientific Reports” In this study, researchers estimated that 80% of patients infected with SARS-CoV-2 experienced at least one long-term symptom, with fatigue being the most common.
December 2023 in “Health Information Jurnal Penelitian” Among adults suffering from post-COVID syndrome, this study reported fatigue as the most common long-term effect, observed in 71.4% of cases, followed by shortness of breath, anxiety/depression, and memory and attention deficits.
15 citations
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March 2020 in “Anais Brasileiros De Dermatologia” This review discusses post-finasteride syndrome, characterized by persistent symptoms despite discontinuation, and concludes that its existence cannot be confirmed; individualized assessment is advisable for those with a history of depression, sexual dysfunction, or infertility.
5 citations
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July 1991 in “Journal of The American Academy of Dermatology” This case report describes a patient with eosinophilia-myalgia syndrome who experienced severe, persistent telogen effluvium.
May 2025 in “The Journal of Rheumatology” This case report describes a woman whose initial presentation of SLE was persistent watery diarrhea, diagnosed as lymphocytic enterocolitis, and shows that immunosuppressive therapy resulted in symptom relief.
This review reports that empirical evidence suggests an overlap between Long Covid, chronic fatigue syndrome, and fibromyalgia, highlighting the need for standardized definitions and rigorous methodologies in related research.
May 2025 in “Life Studies” In this study, lung cancer patients undergoing treatment with immune checkpoint inhibitors and chemotherapy reported high incidence and severity of symptoms such as fatigue, drowsiness, and loss of appetite, which were most prominent and distressing throughout the treatment cycles.
26 citations
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December 2019 in “Neurobiology of Stress” This review discusses adverse effects of 5 alpha-reductase inhibitors, particularly persistent side effects such as post-finasteride syndrome, and highlights the need for further investigation.
11 citations
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August 2019 in “BMJ” This article reviews ongoing concerns about the safety of 5α-reductase inhibitors like finasteride, highlighting the lack of long-term data on persistent depression and sexual side effects after drug discontinuation; no new clinical results are reported.
7 citations
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January 2019 in “The Aging Male” This article discusses post-finasteride syndrome as a distinct syndrome related to prolonged use of 5α-steroid reductase inhibitors, noting persistent side effects even after discontinuation and no new research results are reported.
2 citations
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March 2018 in “Clinical Nutrition ESPEN” This study among ethnic Saudi Arabian women concluded that symptoms like muscle cramps, fatigue, mood swings, hair loss, back pain, and weight gain were more common in those with lower vitamin D levels.
1 citations
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January 2024 in “Journal of Community Medicine & Public Health” In this study, researchers observed that low-risk COVID-19 hospital staff experienced similar persistent symptoms for at least 30 days after discharge, suggesting the need for targeted monitoring and parameter indicators post-infection clearance.
March 2026 in “RS Global journals (RS Global Sp. z O.O.)” This review reports that while finasteride effectively treats androgenetic alopecia and benign prostatic hyperplasia, persistent adverse effects on sexual, psychological, and metabolic health have been noted, highlighting the need for ongoing research and careful risk assessment for safer clinical usage.
July 2022 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” This study found that most women who recovered from COVID-19 in one Brazilian neighborhood experienced lingering symptoms like fatigue and headache, with few undergoing rehabilitation.
August 2016 in “Journal of Investigative Dermatology” This study observed that uncommon finasteride side effects included melasma, dry skin, tinnitus, postural hypotension, and oral lesions, with some symptoms persisting after treatment cessation.
1 citations
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October 2023 in “Romanian Journal of Morphology and Embryology” This review analyzed 109 articles to classify skin lesions associated with COVID-19 and their frequency during the disease, but found no conclusive evidence on long-term persistence of specific types due to rarity.
March 2026 in “Cancer Diagnosis & Prognosis” In this study, researchers used a patient-reported outcome questionnaire to assess long-term adverse effects in breast cancer patients undergoing chemotherapy, finding persistent symptoms like neuropathy, dysgeusia, insomnia, and nail loss. Peripheral neuropathy was notably prolonged in those receiving anthracycline- and taxane-based regimens compared to docetaxel/cyclophosphamide.
February 2026 in “Journal of Dermatology and Skin Science” This review suggests a causal relationship between finasteride, used for hair loss, and persistent neuropsychiatric side effects like depression, citing evidence that fulfills key causality criteria and calls for cautious use along with strengthened regulatory oversight.
November 2025 in “Journal of Saidu Medical College Swat” In this case report, a 2.5-year-old boy with biotinidase deficiency, initially misdiagnosed due to overlapping symptoms, showed dramatic improvement in several clinical areas after starting biotin supplementation, but persistent sensorineural hearing loss underscored the importance of early diagnosis for preventing irreversible complications.
September 2025 in “BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY” In this review, researchers explored the complex mechanisms behind chemotherapy-induced side effects like nausea, fatigue, and hair loss, and discussed potential strategies using natural agents to manage these toxicities, improving understanding for targeted adjunct therapies.
May 2025 in “The Journal of Rheumatology” This case report highlights the rare occurrence of overlapping syndromes including SLE, RA, and AAV in a patient with discoid lupus erythematosus, noting the persistent role of prior viral infection remains unclear.
January 2024 in “Wiadomości Lekarskie” In this study, researchers analyzed the clinical phenotype and primary pathogenic links in patients who survive the acute phase of a critical illness and rely on prolonged intensive care, finding that these patients show persistent inflammation, nutritional deficiencies, and other chronic complications over time.
This study concludes that one year after COVID-19 infection, patients in Northeast Brazil showed improvements in quality of life, although some symptoms such as anxiety and memory loss persisted.
May 2024 in “Journal of clinical case studies reviews & reports” This case report detailed a unique instance of hypopituitarism in a 65-year-old male presenting with symptoms including nausea, vomiting, and fatigue, attributed to secondary adrenal insufficiency, which improved following appropriate cortisol treatment.
This observational study reviewed thyroid eye disease patients treated with teprotumumab at one center, reporting common side effects like fatigue and dry eye symptoms, with serious adverse events including two cases of blood clots and one pulmonary embolism.
September 2023 in “Deleted Journal” This study, conducted at the Surgical Outpatient Clinics of the Medical Research Institute in Alexandria, Egypt, found that post-bariatric surgery patients commonly experienced gastrointestinal and dermatological issues, fatigue, impaired physical activity, and psychological conditions like anxiety within the first year after surgery.