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Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Over half of the adult women with acne in the study had higher than normal levels of male hormones, especially DHEA.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Rosiglitazone may be better than metformin for insulin resistance in PCOS, but more research is needed on certain biomarkers.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Fat-related cells are important for initiating hair growth.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

MED1 affects skin wound healing differently in young and old mice.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

CBD can either reduce inflammation and not affect hair growth at low levels or inhibit hair growth at high levels.

Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.

The RORα gene is active in different parts of cashmere goat hair follicles and may be influenced by melatonin, especially in December when hair growth changes.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.