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Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Scientists created stem cells that can grow hair and skin.

Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Fatty acid transport protein 4 is essential for skin and hair development.

Skin fat helps with body temperature control and has other active roles in health.

Lower SHBG levels may increase the risk of PCOS.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Type 2 diabetes, bacterial scalp infections, and tight hairstyles like braids and weaves are linked to a higher risk of a scarring hair loss condition in African American women.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Lamins are vital for cell survival, organ development, and preventing premature aging.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

SHBG may be a useful early indicator and treatment target for PCOS.

Researchers found 15 new genetic links to skin traits in Japanese women.