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Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Scientists created stem cells that can grow hair and skin.

Fatty acid transport protein 4 is essential for skin and hair development.

Lower SHBG levels may increase the risk of PCOS.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Lamins are vital for cell survival, organ development, and preventing premature aging.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Melatonin improved mental health and metabolism in women with PCOS.

FA2H is essential for normal fur and sebum production in mice.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.