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Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Recognizing rare causes of MASLD is crucial for effective treatment and preventing complications.

Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.

A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Adrenal disorders can cause lasting brain and behavior issues in children.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Melatonin may protect hair follicle cells from damage caused by a chemotherapy drug.

Lichen planopilaris is a rare, chronic condition causing hair loss, mainly in middle-aged women, and early treatment is important to prevent permanent baldness.

Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Lipin-1 is important for skin cell differentiation and skin barrier function.

Tofacitinib can help hair grow back in alopecia patients but hair loss might return if the dose is lowered.

Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

Rosiglitazone may be better than metformin for insulin resistance in PCOS, but more research is needed on certain biomarkers.

Frontal fibrosing alopecia is a challenging hair loss condition with no known cause or definitive treatment.