This study found that, compared to oxidative treatments, reductive perm-waving more severely impacts the intermediate filaments in European human hair, while both treatments alter denaturation kinetics in a first-order manner.
73 citations
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January 1994 in “European Urology” This study found that finasteride significantly reduced serum dihydrotestosterone levels, confirming its efficacy as a 5a-reductase inhibitor, while Permixon showed no effect in healthy male volunteers.
This study found that adding Rosehip extract to permanent waving products with cysteine improved waving efficiency and reduced hair damage compared to thioglycolate-based products.
30 citations
,
March 2016 in “European Journal of Pharmaceutical Sciences” This study found that using drug microplates in transdermal finasteride films enhances aqueous solubility and skin permeation compared to films with pure finasteride.
December 2023 in “Journal of materials chemistry. B” This study found that a nanoemulsion containing perfluorooctyl bromide effectively increased oxygen levels in an anoxic environment, enhancing hair dermal papilla cell growth and significantly promoting hair organ elongation.
In this experimental study, mixing temperature and rate were found to significantly influence cream's physical properties, with mixing rate affecting spreadability and temperature affecting viscosity.
September 2020 in “Benha Journal of Applied Sciences” This study found that scanning electron microscopy revealed significant hair shaft changes in women using straighteners, but not in those using hair dye, suggesting its utility in assessing chemical treatment effects on hair.
3 citations
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July 2023 in “Skin Research and Technology” This study found that instrumental measurement methods effectively verified the efficacy of hair care products in repairing slightly damaged hair, showing consistent results with sensory assessments of gloss and frizz, and offering benefits like accuracy and quantifiability.
7 citations
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October 2017 in “Artificial Cells Nanomedicine and Biotechnology” This research observed that finasteride-loaded ethosomes showed improved permeation across rat skin and human cadaver scalp skin compared to unencapsulated finasteride, potentially enhancing delivery to hair follicle units.
2 citations
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May 2006 in “Journal of Separation Science” This study describes a capillary GC method for accurately measuring spermidine levels in hair lotions, confirming its precision and specificity for this application.
33 citations
,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” This study found that porcine ear skin is more suitable than excised human skin for investigating the efficacy of barrier emulsions in preventing pollen allergen penetration due to its lack of tissue contraction.
2 citations
,
December 2021 in “Pharmaceutics” This study demonstrated that a finasteride-loaded proniosome significantly enhanced transfollicular delivery and hair growth in mice without causing skin irritation, with effects comparable to a 2% minoxidil solution.
August 2025 in “Y HOC TP HO CHI MINH” In this study on Swiss albino mice, researchers reported that perilla leaf extract stimulated hair growth similarly to minoxidil, counteracting hair loss induced by testosterone injections.
9 citations
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August 2005 in “Experimental Dermatology” In this study, the researchers report that a modified epimorphin-derived peptide shows potential for hair follicle regeneration, especially when used with 1% minoxidil in mice.
October 2023 in “Journal of Molecular Liquids” This study demonstrated that imidazole-based ionic liquids, particularly [Emim]DEP, effectively dissolved yak hair keratin, maintaining its structure better than other tested solvents, and also performed well on human hair and goat wool, with consistent performance even after five recycling cycles.
11 citations
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April 1999 in “Dermatologic Clinics” This review covers different hair transplantation techniques and compares their cost-effectiveness and potential results but presents no new research findings.
March 2023 in “JIIS (Jurnal Ilmiah Ibnu Sina): ilmu farmasi dan kesehatan” This study concluded that the optimum biotin microemulsion hair tonic composition involves span 80 (20%), tween 80 (9.47%), and PEG 400 (5%), providing favorable viscosity and globule size.
October 2019 in “Tishreen University Journal -Medical Sciences Series” In this study, PRP injections were found to significantly increase hair density in men with androgenetic alopecia, with a 19.17% average improvement maintained over six months and minimal side effects.
This study found that new methods for isolating human dermal papilla cells were more efficient than traditional methods, maintaining higher levels of specific markers and improving the cells' research potential.
2 citations
,
January 2016 in “Archives of Aesthetic Plastic Surgery” This article reviews methods for restoring the temporal peaks of hair and highlights a technique that produces variable density for a more natural look, but reports no new clinical results.
August 2024 in “Cosmetics” In this study, a bleaching protocol was developed to evaluate hair repair products, revealing that K18® and Olaplex® improve hair brightness and lightness, with distinct impacts on hair fiber properties.
16 citations
,
March 2009 in “Skin Pharmacology and Physiology” This study found that the penetration enhancer SEPA™ significantly increased both the speed and amount of hair growth from minoxidil in balding stumptail macaques compared to Rogaine®.
3 citations
,
September 2015 in “Plastic and reconstructive surgery/PSEF CD journals” Low-dose pulsed electric fields in a rat model shifted hair follicles from resting to active growth, with voltage as the most influential factor.
10 citations
,
January 2014 in “Chemical and Pharmaceutical Bulletin” This study found that hair follicle-plugging reduced skin permeation of certain model drugs, with effects varying based on EtOH pretreatment and the drug being evaluated.
5 citations
,
August 2014 in “Pharmaceutical Development and Technology” In this study, the researchers reported that while both propylene glycol and sodium lauryl sulfate enhanced finasteride's skin deposition, ethanol was the only effective enhancer of finasteride's permeation through the skin.
May 2009 in “International Journal of Cosmetic Science” In this study, permanent waving treatments, especially those using lotion B and repeated procedures, were found to significantly damage hair protein content and physical properties.
In this study, perilla seed extract obtained through supercritical fluid extraction was found to promote hair follicle cell proliferation and downregulate key genes linked to androgenetic alopecia, showing potential as a natural treatment for hair loss in vitro.
3 citations
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September 2018 in “Current Drug Delivery” This study found that a finasteride topical gel formulation using propylene glycol and Tween® 80 showed significantly enhanced permeation compared to a control formulation without these enhancers.
20 citations
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July 1988 in “Clinics in dermatology” This article reviews the current practices and interpretations of research data on permanent waving and hair straightening, but does not present any new research findings.