86 citations,
July 1990 in “British Journal of Pharmacology” Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
20 citations,
January 2022 in “Polymers” Nanoparticles added to natural materials like cellulose and collagen can improve cell growth and wound healing, but more testing is needed to ensure they're safe and effective.
68 citations,
July 2011 in “Journal of Biochemistry/The journal of biochemistry” New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.
2 citations,
March 2020 in “International Journal of Molecular Sciences” Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
23 citations,
February 2020 in “PLOS genetics” Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.
1 citations,
January 2024 in “Pharmaceuticals” A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.
47 citations,
October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
47 citations,
June 2019 in “Nature Communications” Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
November 2023 in “International Journal of Pharmaceutics” New hair loss treatment using marine collagen and dissolvable needles improves hair growth.
127 citations,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
September 2024 in “Journal of Skin and Stem Cell” MMP® with minoxidil may improve hair growth in chronic telogen effluvium.
26 citations,
September 2012 in “Cell Reports” B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
49 citations,
July 2000 in “Journal of Histochemistry & Cytochemistry” POMC-derived peptides are important for skin functions like immune response and stress management.
4 citations,
June 2002 in “Clinical and experimental dermatology” Effective treatment for hidradenitis suppurativa varies, with antibiotics commonly used and surgery as an option, but no single method is universally successful.
12 citations,
June 2011 in “Han-guk sikpum gwahakoeji/Han'gug sigpum gwahag hoeji/Han-guk sikpum gwahak hoeji” Lactobacillus plantarum-fermented plant extracts promote hair growth and thickness.
34 citations,
January 1989 in “Toxicologic Pathology” A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
March 2002 in “Clin-Alert” In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.
70 citations,
July 2020 in “Pharmacological Reports” Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.
31 citations,
January 2017 in “Phytotherapy Research” Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.
55 citations,
May 2014 in “Journal of feline medicine and surgery” Combining systemic and topical treatments, guided by weekly fungal cultures, effectively treats cat ringworm.
15 citations,
March 2012 in “British journal of dermatology/British journal of dermatology, Supplement” Using specific cleansers and moisturizers with niacinamide improves men's skin hydration and health.
1 citations,
December 2022 in “Applied Sciences”
PEGylated liposomal doxorubicin improves cancer treatment effectiveness and reduces side effects like heart damage and hair loss.
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Semecarpus anacardium leaf extracts may offer safe, effective cancer treatment alternatives.
127 citations,
June 2006 in “International Journal of Pharmaceutics” Liposomes and niosomes improve finasteride delivery for hair loss treatment.
22 citations,
October 2018 in “Aesthetic Plastic Surgery” Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.
39 citations,
June 2017 in “Scientific Reports” Different lab conditions and light treatment methods change how human skin cells respond to light therapy.
39 citations,
November 2013 in “European journal of pharmaceutics and biopharmaceutics” Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
63 citations,
February 2013 in “Human cell” PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.
17 citations,
May 2011 in “Gene Therapy” Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.