3 citations
,
March 2005 in “Iranian Journal of Pharmaceutical Sciences” This study demonstrated that liquid-state vesicles may reduce the absorption of finasteride through the skin while increasing its concentration and retention in the dermis layer in hamster models.
2 citations
,
August 2019 in “International Journal of Applied Pharmaceutics” This study explored the use of SOD-loaded niosomes as carriers to enhance the delivery of superoxide dismutase into hair follicles on guinea pig skin, finding that niosomes improved SOD penetration and preservation compared to free SOD, suggesting their potential as effective delivery vehicles.
March 2023 in “Asian journal of beauty & cosmetology” This study found that applying a keratin solution improved tensile strength, reduced absorbance, and increased gloss in damaged hair compared to untreated hair.
May 2026 in “Advanced Pharmaceutical Bulletin” In this study, black cumin oil-based nanostructured lipid carriers enhanced the delivery and effectiveness of fluticasone for psoriasis in a mouse model, improving skin targeting, inflammation reduction, and permeability compared to standard cream.
July 2025 in “Journal of Investigative Dermatology”
October 2022 in “Journal of Kermanshah University of Medical Sciences” The researchers reported that caprylic acid effectively enhances the permeability and diffusion of minoxidil through rat skin compared to other penetration enhancers.
January 2020 in “Acta dermato-venereologica” People with certain hair disorders may also have missing permanent teeth.
April 2016 in “Journal of Investigative Dermatology” This pilot study suggests that autophagy is crucial for anagen maintenance in human hair follicles, and targeting this process may help manage hair growth disorders.
April 2016 in “Journal of Investigative Dermatology” This study found that increasing En1 expression in mouse epidermis can convert cutaneous appendages to eccrine sweat glands, suggesting a role for En1 in eccrine gland development.
March 2014 in “Journal of the American Academy of Dermatology”
January 2013 in “Sen'i Gakkaishi” This study found that microfibrils play a crucial role in shaping permanent waves by thioglycolic acid, and treating damaged hair with hydrolyzed keratin improved both waving efficiency and hair damage.
23 citations
,
June 2014 in “Journal of Pharmaceutical Sciences” This study found that the HPCH-based formulation P-08–016 may facilitate finasteride deposition in the dermis, potentially offering an alternative to systemic therapy by minimizing systemic absorption.
12 citations
,
January 2023 in “AAPS PharmSciTech” 2 citations
,
January 2006 in “Publicatio UEPG Ciencias Biologicas e da Saude” This review discusses the potential of dental stem cells from deciduous and permanent teeth for tissue regeneration and reports no new experimental results.
This study found that the RN-Lip co-delivery system enhanced the stability and skin permeation of retinol and niacinamide, leading to improved anti-aging and skin-brightening effects in vitro.
January 2024 in “UVic’s Research and Learning Repository (University of Victoria)” This project report reviews six experimental 3D bioprinting methods for cultivating artificial hair follicles, noting significant challenges such as method complexity, low output, and delayed approval for human trials, while proposing a potential solution for creating a permanent hair system on the scalp.
January 2021 in “Figshare” This study found that Coenzyme Q10 delivered through transethosomes improved clinical outcomes for androgenic alopecia patients compared to CoQ10 solution.
January 2023 in “Pharmaceutics” In this study, researchers developed a new topical atraric acid formulation, AA-TF#15, which showed a significantly higher drug penetration and increased hair regrowth in mice compared to minoxidil and finasteride treatments, suggesting its potential effectiveness for treating scalp androgenic alopecia.
7 citations
,
October 2024 in “AAPS PharmSciTech” This study developed a caffeine-loaded solid lipid nanoparticle gel, observing significant reduction in subcutaneous fat tissue thickness in histological tests compared to an untreated group, suggesting it could effectively treat cellulite as a promising nanocosmeceutical gel.
3 citations
,
September 2018 in “Current Drug Delivery” This study found that a finasteride topical gel formulation using propylene glycol and Tween® 80 showed significantly enhanced permeation compared to a control formulation without these enhancers.
34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.
November 2024 in “Journal of Investigative Dermatology” Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.
192 citations
,
January 2018 in “Burns & Trauma” This review discusses the advancements in biologic skin substitutes for wound treatment and their potential in enhancing cutaneous regeneration but reports no new clinical results.
124 citations
,
January 1993 in “The Prostate” Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
95 citations
,
July 2015 in “European journal of pharmaceutics and biopharmaceutics” This review discusses the application of lipid nanoparticles for enhancing drug delivery through hair follicles and reports no new clinical results, emphasizing the potential role of sebum-like lipids in this context.
90 citations
,
July 2008 in “Dermatologic therapy” This article reviews lichen planopilaris, a chronic scarring alopecia, and explores recent treatment developments, but it reports no new clinical results.
84 citations
,
April 2015 in “Cosmetics” This review discusses various types of hair dyes, their mechanisms of action, molecular structures, application methods, and formulation aspects, but reports no new research findings.
80 citations
,
March 2000 in “Journal of cutaneous pathology” This study found that the Verhoeff-Van Gieson stain effectively distinguishes scarred from non-scarred dermis and aids in classifying types of permanent alopecia based on elastic tissue patterns.
73 citations
,
May 2011 in “Annals of Epidemiology” This study found that childhood use of hair oils and perms was associated with earlier onset of menarche among women of various racial and ethnic backgrounds.
63 citations
,
August 1996 in “Forensic Science International” In this study, bleaching and perming were found to significantly reduce opiate concentrations in both spiked and naturally opiate-positive human hair samples.