January 2023 in “Fashion and textiles” This study found that hair dyed with anionic basic hair dye lost more color after shampooing compared to cationic and nonionic dyes, with alkaline shampoo increasing this effect.
October 2022 in “Hair Transplantation” This review discusses scalp micropigmentation for hair loss and scarring and reports no clinical results; the authors highlight its use as both a standalone and adjunct treatment.
October 2022 in “Chinese Journal of Dermatology” This study observed that skin dryness does not seem to indicate impaired epidermal barrier function, as there was no negative correlation between stratum corneum water content and transepidermal water loss.
January 2022 in “OPAL (Open@LaTrobe) (La Trobe University)” This study used advanced optical imaging techniques to investigate nanoparticle and dye penetration in human skin, finding that nanoparticles mainly resided in the stratum corneum and accumulated in skin folds and hair follicles, while highlighting that sunscreen-based nanoparticles appear unlikely to pose safety concerns.
August 2021 in “Institutional Repositories DataBase (IRDB)” This study found that rubbing the skin increased caffeine permeation significantly, while rhododendrol showed no enhancement from rubbing, likely due to different distribution patterns in the skin layers.
January 2018 in “Iranian Journal of Pharmaceutical Sciences” In this laboratory study, eucalyptus oil, menthol, and urea were found to enhance the skin permeability of minoxidil in rat skin by increasing flux and diffusion coefficients compared to untreated skin.
December 2017 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” This report describes a case where a woman developed permanent alopecia after chemotherapy with taxanes for breast cancer, and she showed favorable response to 6 months of minoxidil topical treatment.
Using silicon circular iron on Korean women's hair increases hair thickness the most.
January 2014 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” Laser treatment can improve the delivery of hair loss drugs into the skin and hair follicles.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” This study found that Carthamus tinctorius extract significantly increased the length of cultured hair follicles and may be a promising topical agent for hair growth promotion with high skin permeation.
January 2009 in “The Chinese Journal of Modern Applied Pharmacy” This study concluded that QSPR models effectively predict drug skin penetration, with the Potts-Guy model showing the highest predictive accuracy for the drugs tested.
January 2022 in “Advanced Pharmaceutical Bulletin” This study found that clove oil and LPGSE pretreatment increased finasteride skin permeability, while extending urea pretreatment reduced its penetration.
130 citations
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August 2020 in “Drug Design Development and Therapy” This review discusses various nanoparticles used to enhance skin permeation and target delivery to skin organelles, but reports no new experimental results.
84 citations
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July 2008 in “Aaps Pharmscitech” Ethosomes improve finasteride delivery through skin for hair loss treatment.
71 citations
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June 2007 in “Bioorganic & Medicinal Chemistry Letters” This study found that PLGA nanospheres improved scalp-pore permeability and enhanced hair growth activities in mice, suggesting their potential as drug delivery carriers for hair growth ingredients.
58 citations
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March 1985 in “Journal of The American Academy of Dermatology” This review discusses the historical, legal, and clinical aspects of electrolysis and thermolysis, highlighting potential risks due to the lack of standardized training for electrologists in the United States, but reports no new clinical results.
16 citations
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August 2014 in “Archives of Pharmacal Research” This study found that surface-modified liquid crystalline nanoparticles significantly enhanced skin permeation of finasteride and dutasteride compared to unmodified nanoparticles, suggesting potential for improved treatment efficacy in androgenetic alopecia.
16 citations
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March 2008 in “International journal of pharmaceutics” This study found that formulation factors like pH, viscosity, and chemical enhancers can significantly influence intrafollicular hydrocortisone permeation in vitro, with higher pH and enhancers reducing follicular contribution.
14 citations
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May 2014 in “Archives of plastic surgery” This study found that among Korean males with male pattern baldness, hair loss mostly progresses within 6 cm from the parietal whorl towards the occipital side.
13 citations
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November 2017 in “BMC Veterinary Research” This study suggests that topically applied fusidic acid may penetrate only the most superficial layers of canine skin but can reach sufficient concentrations to potentially treat infections caused by pathogenic staphylococci.
12 citations
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March 2020 in “Journal of Bioactive and Compatible Polymers” This study found that finasteride- and minoxidil-loaded nanoparticles in a gel improved skin permeability and drug retention, suggesting a promising approach for topical alopecia treatment with reduced dosing frequency and side effects.
12 citations
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December 2017 in “Food and chemical toxicology” This study found that mixtures used in permanent hair dyes had irritant effects on reconstructed human epidermis, while individual ingredients alone did not.
12 citations
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April 2015 in “BMC research notes” This study found that root hairs in maize, wheat, and finger millet continued to grow beyond the typical root hair zone when grown with the Turface® fertigation system, highlighting potential for understanding root hair dynamics and crop improvement.
9 citations
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July 2022 in “Journal of Cosmetic Dermatology” In this study, an ammonia-free and PPD-free permanent hair dye was tested on 50 ethnically diverse females, showing no cases of contact dermatitis and significant improvements in hair shine, color, moisturization, porosity, and combability after two dyeing sessions.
5 citations
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April 2023 in “Pharmaceuticals” This study found that cubosomes combined with dissolving microneedles enhanced transdermal penetration and hair growth efficacy of beta-sitosterol for treating alopecia.
5 citations
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February 2010 in “Drug development and industrial pharmacy” This study found that vesicles formed with behenyltrimethylammonium chloride, stearic acid, and hinokitiol significantly improved skin permeation of hinokitiol in vitro, which may aid in hair growth promotion.
4 citations
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May 2022 in “Future Journal of Pharmaceutical Sciences” This study found that a melatonin-loaded microemulsion exhibited controlled release and significant stratum corneum deposition in ex vivo permeation tests, suggesting its potential for further evaluation in treating androgenic alopecia.
3 citations
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May 2019 in “Journal of Cosmetic Dermatology” This study suggests that the dipeptide Pro-Ile has FGF18-like activity, can penetrate model human epidermis, and may have potential as a cosmetic ingredient for skin and hair regulation.
3 citations
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April 2015 in “International research journal of pharmacy” This study concluded that the follicular route is a significant pathway for delivering gentamicin through the skin, as demonstrated by higher drug permeation in non-plugged pig's ear skin compared to plugged skin.
3 citations
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January 2004 in “Zhōnghuá yàoxué zázhì” In this study, ethosomes were found to significantly enhance the transdermal penetration and skin accumulation of finasteride compared to liposomes and other control solutions.