1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
65 citations,
April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
48 citations,
June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
9 citations,
August 2021 in “Biological Chemistry” ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
7 citations,
March 2017 in “Journal of dermatology” The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.
4 citations,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
50 citations,
November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
18 citations,
May 2013 in “Cutaneous and Ocular Toxicology” The cancer drugs bortezomib and lenalidomide cause skin side effects in many patients.
August 2024 in “Nature Communications” Softer hydrogels help wounds heal better with less scarring.
47 citations,
August 2016 in “American Journal Of Pathology” Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
99 citations,
May 2013 in “Familial cancer” People with Birt-Hogg-Dubé syndrome often have lung problems and delayed diagnosis, and better recognition of CT scan signs could improve diagnosis and management.
29 citations,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
8 citations,
June 2022 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.
7 citations,
July 2013 in “InTech eBooks” Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.
6 citations,
February 2023 in “Biomaterials Research” Special gels help heal diabetic foot sores and reduce the risk of amputation or death.
December 2021 in “Journal of clinical images and medical case reports” PRP generally shows better results for hair regrowth than mesotherapy, but more research is needed.
136 citations,
May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
65 citations,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
6 citations,
July 2019 in “Experimental Dermatology” Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.
8 citations,
June 2016 in “Journal of Cutaneous Pathology” Two women were diagnosed with a rare melanoma that looked like hair loss but was actually a type of skin cancer.
37 citations,
July 2016 in “Current Opinion in Cell Biology” Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
23 citations,
January 2021 in “Scientific Reports” Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.
6 citations,
September 2009 in “European journal of histochemistry” CD90 is present on specific cells in dog hair follicles.
1 citations,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
254 citations,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
9 citations,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
January 2018 in “Springer eBooks” Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.
85 citations,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.