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This study found that trichodynia is associated with both peripheral and central sensitization, potentially linked to hair cycle abnormalities and chronic pain through proinflammatory agents.

This review discusses the multifaceted roles of neurotrophins, especially nerve growth factor (NGF), in the development and function of nociceptors and reports no new clinical results.

This study suggests that human placenta hydrolysate reduces CFA-induced inflammatory pain in mice by inhibiting pro-inflammatory cytokines and protecting peripheral nerves.

This study found that alopecia areata patients who responded poorly to topical immunotherapy had impaired peripheral blood mononuclear cell responses to T-cell stimulants.

This case report describes a 24-year-old woman with androgenetic alopecia who developed sensitivity to topical minoxidil and later to saw palmetto after using a minoxidil and retinoic acid preparation.

Alopecia areata patients have more activated T cells in their blood, which may help in developing treatments.

This study proposes that intranasal exposure to PTx and autoantigen in an animal model can trigger autoimmune disease, supporting the idea that subclinical nasal colonization by BP may cause alopecia areata.

This review discusses neuroimmune communication in skin disorders and peripheral neuropathic pain, highlighting the complex interactions between sensory neurons and immune cells; it reports no new clinical results but suggests potential future therapies.

This study established a new mouse model for TCE-induced skin sensitization and reported that proinflammatory cytokines TNF-α, IFN-γ, and IL-2 significantly contribute to this sensitization process.

This review discusses the complex links between polycystic ovary syndrome, insulin resistance, and potential metabolic risks starting in adolescence, noting the need for early screening and treatment but reports no new clinical results.

In this case report, tofacitinib was initiated in a 20-year-old female with alopecia universalis resistant to topical treatments, but resulted in a mild peripheral neuropathy side effect.

The study introduced an advanced skin model, ImmuSkin-MT, which effectively distinguished between different strengths of skin sensitizers by mimicking the interaction of immune cells in skin tissue.

This chapter covers various dermatological drugs, cosmetics, and topical agents, focusing on the properties and uses of propolis, but does not present new clinical findings.

This review discusses common causes of alopecia in children, such as telogen effluvium and alopecia areata, and highlights diagnostic and therapeutic challenges, but presents no new clinical results.

This study found that systemic ovalbumin–aluminum sensitization followed by cutaneous challenge in mice induced thermal hyperalgesia, increased spinal cord gliosis, and sprouting of nociceptive fibers, along with elevated mast cell and nerve profile densities in the skin compared to controls.

This review discusses the mechanisms of platinum-induced peripheral neuropathy related to reactive oxygen species and explores potential antioxidant therapies and nanotechnology approaches, but reports no new clinical results.

This review discusses the potential of curcumin and its formulations to mitigate neuropathic and postoperative pain, highlighting positive outcomes in preclinical and clinical studies but noting the need for further clinical research.

Contact immunotherapy can change immune responses in alopecia areata, suggesting new treatment targets.

In this study, an expert panel established a consensus guideline indicating that photobiomodulation is a safe and effective treatment for various conditions, including peripheral neuropathy and androgenic alopecia.

In this narrative hypothesis-driven overview, the authors propose reframing rosacea as a neuroimmune disorder, highlighting the interconnected role of the skin-gut-brain axis, particularly central nervous system involvement alongside gut microbiota and neurogenic inflammation, to emphasize the need for multidisciplinary therapeutic approaches.

This review discusses current and emerging therapies for alopecia areata, highlights the challenges in managing this chronic disease, and emphasizes the importance of addressing its psychosocial impacts; it reports no new clinical results.

This review discusses the potential therapeutic effects of targeting the endocannabinoid system for chemotherapy-induced peripheral neuropathy and reports no new clinical results, highlighting the need for ongoing research.

This editorial reviews the concept of central sensitization and central sensitivity syndromes, discussing their potential role linking various chronic conditions, but it reports no new clinical findings.

This study hypothesized that finasteride administration may increase stress-induced amphetamine locomotor sensitization due to its impact on brain reward systems involving the neurosteroid allopregnanolone.

This review explores the interactions between the skin, peripheral nervous system, and immune system and reports no new results; the authors highlight the importance of understanding these connections for various skin conditions.

This study found that intradermal injections of Profhilo® significantly reduced skin inflammation and pain, while altering spinal cord markers in mice with ovalbumin-induced atopic dermatitis, suggesting potential therapeutic benefits for inflammatory skin conditions involving both peripheral and central processes.

This study found that carvacrol activates the TRPV3 ion channel by binding to a specific pocket formed by the S2-S3 linker, providing insight into its role in skin sensitization and potential for designing specific modulators.

This review discusses pharmacologic treatment options for muscle-related pain conditions and notes that there is strong evidence for the efficacy of tricyclic antidepressants and muscle relaxants in specific myofascial pain syndromes, but not universally.

In this study, a unique form of chronic superficial pyoderma gangrenosum with verrucous and ulcerative lesions was reported to heal without systemic corticosteroids in most patients.

This review examines the causes, assessment, and treatment options for hirsutism but presents no new clinical findings, highlighting the need for further research on managing this condition.