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A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Cannabinoids may help some skin conditions but more research is needed.

Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

A man got six skin cancers within a year after a cell transplant for leukemia but was cancer-free 32 months later; skin checks are important post-transplant.

A 16-year-old boy with lupus had a rare brain artery issue but fully recovered with treatment.

Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.

Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

Sensitive scalp causes discomfort and hair loss, treated with personalized care.

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

Different lab conditions and light treatment methods change how human skin cells respond to light therapy.

Tamsulosin may slightly increase dementia risk compared to other treatments for enlarged prostate.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Exosomes show promise for future tissue regeneration.

Cannabidiol shows promise as an effective treatment for acne.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.