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The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

A mother's diet at conception can cause lasting genetic changes in her child.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Human skin can make serotonin and melatonin.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Nerves are crucial for the regeneration of various body parts in many animals.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Sebocytes play a key role in controlling androgen levels in human skin.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.