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Personalized thiopurine dosing based on NUDT15 genotyping can improve long-term outcomes for ulcerative colitis and Crohn's disease patients.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Microorganism overgrowth and hyperkeratosis may trigger immune reactions causing lichen planopilaris.

A genetic mutation in the DCAF17 gene caused Woodhouse-Sakati syndrome in a Chinese patient from a related family.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Type-2 immunity may influence skin diseases and could be targeted for treatment.

308-nm excimer light therapy helped over a third of treatment-resistant alopecia universalis patients regrow most of their hair.

Iron nanoparticles made from pumpkin extract effectively treated burns and promoted healing in mice.

Apremilast was not effective in treating moderate-to-severe alopecia areata.

Possible link between androgens and COVID-19 severity; more research needed.

Certain genetic variations in the RAB5B gene are linked to a higher risk of polycystic ovary syndrome in Chinese Han women.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Mutations in the CYP21A2 gene are not a major factor in causing PCOS.

Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.

Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.

People with palmoplantar pustulosis, especially with bone issues, have different mouth bacteria compared to healthy people.

COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

The document suggests a personalized treatment plan for alopecia areata based on the patient's age and hair loss severity, using a range of therapies ranked by effectiveness and safety.

A new plant-based treatment was effective for hair regrowth in women with a specific type of hair loss that didn't respond to usual treatments.