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Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

Androgen use may increase the risk of stroke, but more research is needed.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Alopecia areata, a type of hair loss, may be passed through T cells and has genetic links, while treatments vary in effectiveness. Male pattern baldness can be treated with finasteride and is influenced by androgens in hair follicles.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Both drugs lower DHT levels, with GI198745 being more effective.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Finasteride may affect PNMT, causing side effects.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Topical drugs and near-infrared light therapy show potential for treating alopecia.