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Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.

TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

The effects of estrogen on human scalp hair growth are unclear and need more research.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.

Transplanted hair follicles show significant changes after FUE, needing more research.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

New treatments and diagnostic methods for various animal skin conditions showed promising results.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.

Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

Saw palmetto extract may help with hair loss and acne but needs more research on safety and long-term effects.

New therapies are being developed that target integrin pathways to treat various diseases.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

A man's breast enlargement from low-dose finasteride for hair loss didn't go away, even with treatment, and might be more common than reported.