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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Hair growth slows and shedding increases after childbirth, but most women don't experience excessive hair loss.

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.

The conclusion suggests a possible link between iron levels and hair health in women, recommending further research on iron supplementation for hair loss.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.

Combination therapy with steroids and pimecrolimus improved or stabilized hair loss in most patients with Frontal Fibrosing Alopecia, who also had a high rate of hypothyroidism.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

The study concluded that severity of Frontal fibrosing alopecia is not linked to how long someone has it, can start before menopause, and eyebrow loss may be an early sign.

AR gene not major factor in female hair loss; different from male hair loss.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

Potassium levels affect blood sugar and insulin during dialysis, and malnutrition changes children's hair roots.

Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.

Trichoscopy helps diagnose frontal fibrosing alopecia, even with unusual patterns.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

Cimetidine did not reduce hair growth in women with hirsutism.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.

Finasteride 2.5 mg/day can effectively treat female hair loss.

Hair transplantation is the only permanent solution for female pattern hair loss and can greatly improve quality of life with careful planning.