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In this study, the authors concluded that the VCD-induced follicular depletion rat model can effectively simulate the perimenopause transition, with hormonal changes distinguishing early/mid-transition from late transition to estropause.

This review discusses the perimenopause, its symptoms, and management options, emphasizing the role of pharmacists in educating and advising women on treatment strategies and preventive health measures, but it reports no new results.

In this study, combining Kuntai capsules with nilestriol tablets for three months was found to reduce symptoms of perimenopausal syndrome and improve reproductive hormone levels more effectively than nilestriol alone; however, the benefits did not persist significantly beyond three months.

Isoflavones may help with menopause symptoms but could be risky for women with hormone-sensitive cancers.

This case report illustrates that Leydig cell tumors, despite causing significantly elevated androgen levels, can be difficult to localize due to their small size, as demonstrated in a 42-year-old woman whose tumor was only identified after oophorectomy.

The researchers reported that adult menstruating females with chronic telogen effluvium had significantly lower serum zinc levels compared to healthy controls, suggesting an association between decreased zinc levels and CTE.

This article reviews the limited evidence on testosterone therapy for premenopausal women and notes a lack of long-term safety and effectiveness data for this population.

This review reported that Withania somnifera (Ashwagandha) significantly improved symptoms like vasomotor disturbances, psychological well-being, and sleep quality in perimenopausal women and was well tolerated, with largely mild side effects in examined trials.

This case report describes the first known instance of fibrosing alopecia associated with cutaneous lichen planus, suggesting fibrosing alopecia may be a variant of lichen planopilaris.

In this study of premenopausal Iranian women with hirsutism, polycystic ovary syndrome was a common cause and frequently associated with menstrual irregularity, while elevated androgens or hyperandrogenic conditions were also observed.

Hair loss can occur as a side effect of certain breast cancer treatments, but minoxidil can help regrow hair.

This study found that among women with hirsutism, acne was the most common associated feature, and severity varied with related conditions like menstrual irregularities and obesity.

This review found no evidence that DHEA improves quality of life or decreases menopausal symptoms in peri- and postmenopausal women, but it may slightly enhance sexual function compared to placebo.

This study found that the most common skin disorders among perimenopausal Indian women were eczematous and urticaria, potentially linked to heightened sensitivity to environmental factors.

This review discusses the symptoms, diagnosis, and management of polycystic ovarian disease, emphasizing the complex implications of obesity and insulin resistance, and calls for long-term follow-up to assess management strategies.

This review discusses hirsutism management guidelines, recommending androgen testing only for women with abnormal hirsutism scores and advocating for combined therapy approaches depending on severity and underlying conditions, but it reports no new clinical results.

This study found a high prevalence of clinical signs and functional disorders of androgen excess in premenopausal women, with idiopathic hyperandrogenism and idiopathic hirsutism rates similar to PCOS.

This guideline discusses the evaluation and treatment of hirsutism in premenopausal women, recommending oral contraceptive pills or antiandrogens as initial therapies with weak support from low-quality evidence.

This study found that the prevalence of hyperprolactinaemia in healthy premenopausal female blood donors is low and not affected by hormonal contraceptive use, with stress-related factors being the most common cause.

This study found that among premenopausal women with hirsutism, obesity was strongly associated with the severity of the condition, while endocrine test results showed no correlation.

This study found that approximately 26% of women with Type 1 diabetes have undiagnosed androgen disorders, with polycystic ovary syndrome being the most common, particularly in those with premenarcheal onset of diabetes.

This study found that iron deficiency might play a role in the development of telogen effluvium in premenopausal women, highlighting the importance of checking hemoglobin in acute TE and serum ferritin in chronic TE.

Women with premature ovarian insufficiency have a worse cardiovascular risk profile than premenopausal women.

This study reports that oophorectomy significantly reduces serum testosterone levels in postmenopausal women, indicating the postmenopausal ovary's continued production of testosterone.

A young woman developed facial bumps before hair loss, which is unusual for her condition.

The drinkable supplement increased hair growth and was safe for women with hair loss.

This study found a significant association between increased waist circumference and body mass index and female pattern hair loss in premenopausal women, suggesting the importance of screening for metabolic syndrome in these patients.

This study suggests that female sexual dysfunction is not significantly associated with female pattern hair loss, but it may be more strongly influenced by age and parity in premenopausal women.

This study suggests that long-term use of hair dyes may be associated with higher testosterone levels among premenopausal Japanese women.

Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.