21 citations
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June 2022 in “Molecules” This review discusses the phytochemistry and pharmacological activities of Perilla frutescens, detailing its bioactive compounds and their potential health benefits, but reports no new clinical results.
16 citations
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April 2025 in “Foods” This study highlights the diverse applications of *Perilla frutescens* in traditional medicine, cuisine, and industrial settings, noting its significant antioxidant and antimicrobial properties in experimental models, as well as research efforts to enhance its bioactive content and ensure safety and standardization.
13 citations
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December 2017 in “BMC Complementary and Alternative Medicine” In this study, the herbal complex of Houttuynia cordata, Perilla frutescens var. acuta, and green tea promoted hair growth in C57BL/6 mice, enhancing regrowth and follicle development compared to controls.
8 citations
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September 2017 in “Journal of Natural Medicines” This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.
August 2025 in “Y HOC TP HO CHI MINH” In this study on Swiss albino mice, researchers reported that perilla leaf extract stimulated hair growth similarly to minoxidil, counteracting hair loss induced by testosterone injections.
January 2017 in “Figshare” This abstract lists raw data on various hair and skin parameters in mice and reports no new results.
This study found that supercritical fluid extraction of germinated perilla seed significantly promoted hair follicle cell proliferation and gene expression related to hair growth, suggesting its potential as a natural treatment for hair loss.
In this study, perilla seed extract obtained through supercritical fluid extraction was found to promote hair follicle cell proliferation and downregulate key genes linked to androgenetic alopecia, showing potential as a natural treatment for hair loss in vitro.
May 2026 in “Applied Sciences” In this review, the authors reported that sprout extracts, rich in bioactive compounds, show promising effects on skin health, such as enhancing collagen synthesis, improving hydration, and reducing inflammation, though most evidence comes from laboratory and animal studies.
84 citations
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April 2013 in “Applied Microbiology and Biotechnology” This review discusses the current research and development of mannosylerythritol lipids, particularly focusing on their potential commercial applications in cosmetics; it reports no new results.
67 citations
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June 2018 in “Engineering in Life Sciences” This review discusses advancements in plant cell culture technology for producing potent natural cosmetic ingredients and reports no new experimental results.
64 citations
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June 2020 in “PLoS ONE” This study found that red light exposure significantly enhanced the growth, phytochemical content, and therapeutic potential of Eclipta alba callus cultures compared to other multispectral light exposures.
53 citations
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January 2017 in “BioMed research international” This review discusses the importance of omega-3 fatty acids for human health and explores recent advancements in genetically modifying plants to produce these essential nutrients, but reports no new results.
44 citations
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August 2012 in “Journal of Food Science” This study optimized conditions for extracting saponins from Eclipta prostrata, achieving maximum yield with specific ethanol concentration, time, temperature, and liquid/solid ratio.
22 citations
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November 2024 in “Planta” This review highlights the potential of aromatic plants as natural antioxidants in cosmeceuticals, which may combat skin aging and promote rejuvenation by counteracting oxidative stress, offering a natural alternative to synthetic products with benefits like photoprotection and anti-wrinkle effects.
16 citations
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October 2019 in “Biological & Pharmaceutical Bulletin” This study suggests that Houttuynia cordata extract may promote hair growth by stimulating dermal papilla cell proliferation and extending the anagen phase through enhanced energy metabolism and gene expression changes.
10 citations
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August 2024 in “Clinical Cosmetic and Investigational Dermatology” This review reports that natural compounds show promise in slowing skin photoaging by targeting cellular pathways in keratinocytes and fibroblasts. However, comprehensive clinical studies are needed to verify their efficacy and safety.
8 citations
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April 2020 in “Journal of Ethnopharmacology” This review assessed experimental studies on herbs used for alopecia, identifying potential mechanisms involving hair cycle management and keratinocyte processes, but highlighted a need for improved evidence on quality control and toxicity of these herbal treatments.
1 citations
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March 2021 in “Skin health and disease” This review evaluates laboratory models used in androgenetic alopecia research but reports no new findings, emphasizing the potential of human-derived 3-D models for future studies.
1 citations
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January 2017 in “Social Science Research Network” This paper suggests that to better protect traditional and indigenous knowledge, TKDL should expand its database or establish a separate confidential resource for indigenous, tribal, and nomadic communities.
March 2026 in “Aging Research” This review provides a comprehensive synthesis of skin aging research, highlighting the interplay of genetic and environmental factors, cellular mechanisms, and advances in diagnostic and therapeutic strategies, while also addressing current debates and future directions in the anti-aging field.
This research highlights selenium's critical roles in various biological processes and underscores the potential health impacts of both its deficiency and excess, including increased mortality risk, poor immune function, and neurological issues.
March 2024 in “Asian journal of beauty & cosmetology” In this study, Derma Genie™-H001 was shown to reduce inflammation, counteract oxidative and UVB-induced damage, and support hair growth-related gene expression in human dermal papilla cells, suggesting its potential as a functional cosmetic ingredient to alleviate hair loss symptoms.
January 2024 in “Biological & clinical sciences research journal” This review of 355 articles found that apigenin, a compound found in many plants and vegetables, is mainly researched for its anti-inflammatory, neuroprotective, and anti-cancer properties, with enhanced efficacy when combined with allopathic drugs.
April 2023 in “Tikrit journal of pharmaceutical sciences” This pilot study found that ginger may improve hair growth and allow for a reduction in prednisolone dosage by mitigating oxidative stress in patients with alopecia areata over 60 days.
December 2022 in “International Journal of Advanced Research in Science Communication and Technology” This review highlights that while traditional cancer treatments like chemotherapy and radiation therapy come with significant side effects, plant-based medicines offer promising anticancer properties with fewer adverse effects, as endorsed by the World Health Organization.
January 2020 in “Elsevier eBooks” This chapter provides an overview of phytochemicals with properties to combat alopecia and discusses the potential of flavonoids, found in several herbs, as a safer alternative to synthetic hair loss treatments due to their long-term skin compatibility.
August 2025 in “Journal of Cosmetic Dermatology” In this systematic review, researchers examined various treatments for axillary hyperpigmentation, finding that Q-switched Nd:YAG laser and intense pulsed light showed significant improvement with minimal adverse effects; desonide and Cyperus rotundus oil were also notably effective among topical treatments.
17 citations
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September 2024 in “Cosmetics” This study assessed the antioxidant properties and contents of carotenoids and chlorophylls in 10 plant oils, finding fenugreek seed oil to be highest in carotenoids and pomegranate oil most active against free radicals, highlighting their potential as natural materials with antioxidant benefits.
16 citations
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June 2022 in “Agronomy” This study found that the application of plant-derived biostimulants, Trainer® and Auxym®, significantly affected various physiological traits in lettuce, but responses varied depending on the cultivar.