March 2024 in “International Journal of Cosmetic Science” Dandruff is linked to increased T cells and weakened immune protection in hair follicles.
99 citations,
April 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicles help skin immune recovery after UVB exposure.
33 citations,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
5 citations,
December 2021 in “Frontiers in Cell and Developmental Biology” Enzymes called PADIs play a key role in hair growth and loss.
3 citations,
June 2023 in “Medicines” Some antiseizure medications can cause reversible hair loss, with valproate, lamotrigine, and carbamazepine being the most common.
1 citations,
November 2023 in “iScience” A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
October 2024 in “Archives of Dermatological Research” Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.
October 2022 in “IntechOpen eBooks” Hair loss due to scarring can be treated by reducing inflammation, removing scar tissue, and transplanting hair. The Follicular Unit Extraction technique is effective but requires skill and time. Future focus should be on scar-less healing methods.
1 citations,
September 2021 in “Journal of The American Academy of Dermatology” Hair loss in both Androgenetic Alopecia and Alopecia Areata is often accompanied by inflammation around hair follicles, but the location and severity of this inflammation varies.
13 citations,
January 2019 in “Skin appendage disorders” FAPD is a possible diagnosis for hair loss in patients of color and requires multiple evaluations for accurate diagnosis.
68 citations,
May 2012 in “Annals of Oncology” Some breast cancer chemotherapy can cause permanent hair loss.
13 citations,
January 2013 in “International Journal of Trichology” Inflammation around hair follicles may worsen hair loss; evaluating and treating it can improve transplant results.
16 citations,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” The document concludes that there are no reliable treatments for frontal fibrosing alopecia, with only temporary benefits from current options.
29 citations,
September 2014 in “American Journal of Dermatopathology” Horizontal sections of scalp biopsies are good for diagnosing Central Centrifugal Cicatricial Alopecia and help customize treatment.
16 citations,
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Blocking interferon-gamma helps prevent and treat hair loss in Alopecia Areata.
62 citations,
March 2012 in “Journal of the European Academy of Dermatology and Venereology” Using dermoscopy to guide scalp biopsies is an effective way to diagnose cicatricial alopecia.
23 citations,
April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
16 citations,
February 2018 in “Journal of The American Academy of Dermatology” Scalp biopsies from dermatomyositis patients show chronic hair loss without scarring, with mucin and blood vessel changes being very common.
7 citations,
June 2019 in “Cureus” Fractional lasers and microneedling, combined with topical agents, could potentially treat Alopecia Areata effectively, but more research is needed due to limited data.
Afro-textured hair is more fragile and prone to certain scalp conditions, requiring careful treatment and more research for effective management.
8 citations,
January 2017 in “Indian dermatology online journal” Traumatic anserine folliculosis is a skin condition caused by friction, treatable with topical cream and avoiding trauma.
Scarring alopecia, a type of hair loss, is most common in females under 35, often caused by discoid lupus erythematosus and pseudopelade of Brocq. Skin punch biopsy and histopathology are key to identifying its cause.
15 citations,
December 2011 in “Journal of the European Academy of Dermatology and Venereology” Hair loss in systemic lupus erythematosus patients is unique and improves with treatment.
9 citations,
January 2017 in “Dermatology Online Journal” Some hair loss drugs can cause a unique type of hair loss that resembles both psoriasis and alopecia.
3 citations,
October 2019 in “JAAD Case Reports” Two patients with lupus had an unusual type of hair loss not typical for the disease but improved with treatment.
3 citations,
January 2016 in “Dermatology online journal” Some people with lichen planus pigmentosus might later develop frontal fibrosing alopecia.
1 citations,
March 2012 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Dermoscopy helps diagnose frontal fibrosing alopecia by identifying specific scalp features.
January 2023 in “Indian Journal of Dermatology” The study found that Frontal Fibrosing Alopecia in North-East India mainly affects middle-aged women and is often associated with lichen planus pigmentosus.
January 2020 in “Indian dermatology online journal” Alopecia areata can show unusual red-dotted vessels and dithranol treatment may mask typical patterns.
Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.