22 citations,
January 2012 in “Mediators of inflammation” Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
19 citations,
July 2020 in “EBioMedicine” A gene variant increases the risk of a type of hair loss by affecting hair protein production.
19 citations,
January 2015 in “Skin appendage disorders” The report found a new type of hair loss in African-American women that affects more areas of the scalp than previously thought.
15 citations,
February 2020 in “Experimental Dermatology” The document concludes that understanding and treatments for alopecia areata have significantly advanced, now recognizing it as an autoimmune disorder.
14 citations,
April 2016 in “International Journal of Trichology” 12 citations,
January 2020 in “Indian Dermatology Online Journal” The document provided an update on female pattern hair loss (FPHL), discussing its multifactorial etiopathogenesis involving genetic, hormonal, and environmental factors. It reviewed diagnostic methods like trichoscopy and the hair pull test, and explored various treatment options including topical treatments (minoxidil, prostaglandin analogs), systemic treatments (finasteride, spironolactone), and novel therapies (platelet-rich plasma, laser treatments). The document emphasized the significant psychosocial impacts of FPHL, the variable responses to conventional treatments, and the promise of newer approaches and combination therapies.
11 citations,
January 2022 in “Journal der Deutschen Dermatologischen Gesellschaft” Alopecia areata is a chronic condition causing hair loss, with new treatments targeting the immune system showing promise.
10 citations,
January 2021 in “Annals of dermatology/Annals of Dermatology” Nivolumab can cause hair loss as a rare side effect.
10 citations,
January 2012 in “Case reports in medicine” Diphencyprone can cause unexpected and possibly permanent vitiligo.
9 citations,
August 2015 in “Tissue Engineering and Regenerative Medicine” Human skin cell byproducts can potentially be used to treat hair loss and promote hair growth.
8 citations,
December 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
8 citations,
January 2013 in “International journal of trichology” Two people had unusual ring-shaped hair loss due to an autoimmune disorder.
7 citations,
January 2012 in “International Journal of Trichology” Sudden, unusual hair loss may indicate serious underlying health issues.
6 citations,
February 2010 in “Biotechnology and bioprocess engineering” Using umbilical cord stem cells can help create hair-growing tissues more affordably.
4 citations,
May 2022 in “Frontiers in Medicine” About 11% of patients with secondary syphilis had Syphilitic Alopecia, which usually improved with treatment.
4 citations,
August 2007 in “PubMed” A woman lost all her body hair after hepatitis C treatment, but it started to grow back a year after stopping the treatment.
3 citations,
June 2023 in “Medicines” Some antiseizure medications can cause reversible hair loss, with valproate, lamotrigine, and carbamazepine being the most common.
3 citations,
April 2022 in “International Journal of Molecular Sciences” Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
3 citations,
June 2020 in “Cureus” A woman's hair loss led to discovering she had lupus.
2 citations,
June 2023 in “Skin Research and Technology” Yellow dots and short vellus hairs are the most common signs of Alopecia Areata (AA), and trichoscopy can help diagnose AA and track treatment progress.
2 citations,
February 2023 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” For sensitive scalp, treatment is personalized and may include specific medications and hydration, while avoiding stress and irritating products.
2 citations,
January 2023 in “Journal of Clinical Medicine” People with hair loss conditions may also have thyroid disorders, but more research is needed to understand the connection.
2 citations,
July 2022 in “Stem cell research & therapy” A new method quickly and efficiently isolates hair follicle stem cells from adult mice, promoting hair growth.
2 citations,
June 2022 in “International Journal of Molecular Sciences” The study examined the expression of smooth muscle cell-related genes in human dermal sheath cup (DSC) cells and their impact on the outcomes of autologous cell-based therapy for male and female pattern hair loss, involving 32 DSC cell lines from 65 donors. It found that lower levels of smooth muscle cell markers like SRF and CALD1 were associated with better treatment outcomes. CHIR99021 treatment significantly downregulated these markers and upregulated SOX2 and LEF1, suggesting a shift towards dermal papilla cell properties, which are crucial for hair follicle generation. These findings indicate that modulating gene expression in DSC cells could enhance the efficacy of hair loss treatments. Further research with larger sample sizes is needed to validate these results.
2 citations,
December 2021 in “Dermatology and therapy” This systematic review of 22 clinical studies involving 1,127 subjects found that microneedling (MN) is effective in improving hair loss parameters across various hair loss types, particularly when combined with 5% minoxidil. Despite positive outcomes and no serious adverse events, the quality of the data is relatively low due to significant heterogeneity in study designs and procedures. The review calls for more standardized, high-quality research to better understand MN's efficacy and establish best practices.
2 citations,
January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” The most effective way to diagnose non-scarring hair loss is by transverse sectioning, and some cases, particularly in males with inflammation around hair follicles, might be curable.
1 citations,
July 2023 in “International Journal of Molecular Sciences” Treating fat stem cells with low oxygen boosts hair growth cell growth through specific signaling pathways.
1 citations,
February 2023 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Sensitive scalp causes discomfort and hair loss, treated with personalized care.
1 citations,
November 2022 in “Journal of Dermatological Treatment” Platelet-rich plasma can increase hair density and may help treat some skin conditions, but it's costly, not FDA-approved, and needs more research.
1 citations,
January 2022 in “Stem cell biology and regenerative medicine” New methods to test hair growth treatments have been developed.