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Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

The document concludes that follicular unit transplantation offers more natural results and better graft survival than older hair transplant methods.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Careful planning and patient counseling can lead to excellent hair transplant results, often in one or two sessions.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.

New genes and pathways are important for testosterone production and male sexual development.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.

Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.

Skin problems are very common in people with end-stage kidney disease.

The document concludes that good cosmetic outcomes in hair transplantation depend on the surgeon's artistic skill and careful planning.

No cure for female pattern hair loss, but various effective treatments exist.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Doctors need to be better prepared to assess and treat obesity in patients.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Some systemic treatments work for nail psoriasis but can have serious side effects.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.