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Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Cysteine helps maintain keratin production in skin cells even when iron is low.

Behavioral dermatology treats skin problems by considering both emotional and physical factors.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Human hair protein extracts can protect skin cells from oxidative stress.

Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Annexin A2 isoform 2 helps dermal papillae cells grow, affecting hair growth.

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

More research is needed before using brown fat to treat polycystic ovary syndrome.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Scientists created a new 3D skin model from cells of plucked hairs that works like real skin and is easier to get.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.