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Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.

DHT may reduce inflammation caused by certain bacteria in skin cells.

Neurohormones help control skin health and could treat skin disorders.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.

Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.

IGRT resulted in lower acute toxicity for stage III prostate cancer patients.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Different types of stem cells and their environments are key to skin repair and maintenance.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Stress can stop hair growth in mice, and treatments can reverse this effect.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.