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In this study, Ageratum houstonianum ethanolic extract and its active component agerarin were found to promote hair growth and follicle elongation by increasing SCUBE3 expression via activation of MAPK–AP-1 signaling in human dermal papilla cells, suggesting potential therapeutic value for treating hair loss.

This study highlights that niosomes, or non-ionic surfactant based vesicles, offer an advantageous drug delivery system due to their stability, cost-effectiveness, and ability to enhance drug bioavailability and targeting efficiency for various therapeutic agents.

This study found that the petroleum ether extract from the leaves of Hibiscus rosa-sinensis demonstrated more effectiveness in promoting hair growth in rats compared to the extract from its flowers.

This review evaluates and classifies the non-saponin components of Korean Red Ginseng, emphasizing their combined role with saponins in the plant's bioactivity, but reports no new clinical results.

This study utilized a sequence-structure alignment approach to improve the characterization of Class A Rhodopsin GPCR superfamily, including orphan and unclassified receptors, through evolutionary analysis.

This study found that hollow polydopamine nanoparticles enhanced the regenerative potency of the peptide RL-QN15, suggesting potential for improved therapeutic approaches in skin wound healing.

This article reviews mechanisms by which herbal ingredients may stimulate or inhibit hair growth, and it reports no new clinical findings while suggesting potential for developing hair loss treatments.

This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.

This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.

This review summarizes preclinical and clinical information on herbal products for hair loss treatment, highlighting their mechanisms, follicular penetration, and potential side effects, suggesting they may offer alternatives to synthetic drugs with fewer side effects.

This study found that cow placenta extract increased hair follicle size and hair length in mice but was less effective than minoxidil, suggesting potential with further refinement.

This review summarizes existing reports on placenta extract for treating liver injury and discusses its mechanisms but provides no new clinical results.

This study found that a hair serum containing amla extract, freeze-dried coconut water, and selenium significantly improved hair growth rate, density, and reduced hair fall among healthy volunteers over 90 days.

In this review, researchers explore various treatment options for alopecia, focusing on nano-drug delivery systems using plant-based substances, which are potentially effective and less harmful than current treatments, while also highlighting emerging trends such as 3D bioprinting and plant extracts for future therapies.

This review discusses the use of nanomaterials in cosmetics, highlighting their benefits like enhanced stability and skin penetration, while also noting potential health risks and the role of natural ingredients in formulations.

This study found that porcine-placenta-extract-loaded nanoformulated serum improved skin hydration and promoted hair growth, as well as reduced intracellular ROS and inflammation without cytotoxicity in human subjects.

This study found that certain off-label topical therapies, including prostaglandin analogs and polyphenols, improved hair restoration in men with androgenetic alopecia over placebo in the short term, though long-term effects are unknown.

This review discusses techniques and models for assessing hair growth activity but reports no new clinical findings, emphasizing the need for standardization and improved animal models.

This study found that a hydro-alcoholic extract of Roselle petals may reduce free radical production during UV-induced photodecomposition of antibiotics, potentially offering protective benefits for patients using similar topical antibiotics.

This article reviews popular peptides used in cosmetics for wrinkle treatment and presents no new clinical findings.

This study found that while the EtOAc fraction of Centella asiatica had the highest antioxidant activity, it was toxic to human follicle dermal papilla cells, but the EtOH crude extract promoted hair growth by enhancing VEGF expression.

This chapter discusses various substances and therapies for dermatological applications, including heliotherapy, UVB, khellin, and others, but reports no new research findings.

This review discusses various bioactive elements in cosmeceuticals, highlighting their potential benefits, such as anti-aging effects and skin tone improvement, while noting the growing demand due to safety concerns and expanding market opportunities.

This review highlights various alternative and complementary treatments for androgenic alopecia, noting that while only two FDA-approved options exist, increased awareness among dermatologists of supportive evidence for other therapies may better inform patient education.

In this study, onion (Allium cepa) extracts promoted hair growth in an alopecia model in mice, with the effect appearing unrelated to the presence of the polyphenol quercetin.

In this study, a new formulation of human placental extract showed antioxidant and neurite outgrowth activities, significantly reduced hair graying in mice, and alleviated neuropathy symptoms, suggesting potential therapeutic benefits.

In this review, the authors reported that sprout extracts, rich in bioactive compounds, show promising effects on skin health, such as enhancing collagen synthesis, improving hydration, and reducing inflammation, though most evidence comes from laboratory and animal studies.

This study evaluated the antimicrobial activity of Albizia saponaria stem bark against microorganisms causing dandruff and fungal alopecia. It found that the hexane fraction exhibited potent antifungal effects comparable to ketoconazole, highlighting its potential as a natural therapeutic for dandruff.

This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.

In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.