14 citations
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January 2020 in “Evidence-based Complementary and Alternative Medicine” This study found that a newly synthesized peptide from fermented Trapa japonica extract significantly promoted wound recovery and showed antiaging effects in skin cells and a clinical study, suggesting potential as a cosmetic product.
9 citations
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November 2019 in “Scientific reports” This study isolated a bioactive peptide from Trapa japonica fruit and found that it may protect human dermal papilla cells from DHT-induced stress, suggesting potential for biomedical applications.
January 2024 in “Pharmacokinetics and Pharmacodynamics” This review discusses peptide "biogenic stimulants" from human placenta extracts, highlighting their potential wide-ranging clinical applications across multiple diseases, and reports no new clinical results.
March 2025 in “Journal of Cutaneous and Aesthetic Surgery” In this study, three different hair serums were tested for their impact on Telogen effluvium in adult females, finding all effective in reducing hair shedding, with the cytokine-based serum showing the most significant improvement, reducing hair fall by 54.6% without adverse effects.
12 citations
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July 2012 in “Journal of Applied Polymer Science” This study found that applying botanical extracts improved the mechanical properties of bleached hair, reducing its permeability and increasing its crystalline content.
April 2019 in “Journal of Investigative Dermatology” This study reported that a Maca hydrolysate extract protected human hair follicles from oxidative and inflammatory stress and promoted hair growth in ex vivo models, suggesting a potential use for managing hair loss.
36 citations
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October 2015 in “Journal of Cosmetic Dermatology” In this study, a new apple stem cell extract serum significantly improved signs of skin aging and enhanced cell metabolism in human senescent fibroblasts, showing visible effects after one week of use.
6 citations
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December 2019 in “BMC Complementary and Alternative Medicine” This study found that the alcohol extract of Vernonia anthelmintica may counteract stress-induced hair follicle growth inhibition in mice, potentially offering a new approach for treating stress-related hair loss.
July 2019 in “Technology audit and production reserves” This research discusses the formulation of probiotic gel shampoos with whey peptides and plant extracts, highlighting their potential effectiveness and market feasibility in Ukraine.
5 citations
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December 2023 in “Materials” This review paper highlights the development and application of organic and biogenic nanocarriers for delivering bioactives, focusing on eco-friendly and sustainable nanotechnology strategies while addressing challenges like toxicity and paving the way for future innovations in green solution approaches.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review evaluates the efficacy and safety of natural hair growth actives set to enter the 2025–2026 market, noting their potential as alternatives to conventional therapies for alopecia but highlighting formulation challenges that may impact their effectiveness.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review critically evaluated natural hair growth actives for the 2025–2026 marketplace and found they show potential as alternatives to conventional therapies for androgenetic alopecia, with favorable safety and patient acceptance, though challenges such as formulation instability and limited follicular penetration remain.
This literature review examined topical treatments for various alopecia types, finding that minoxidil and corticosteroids are effective for multiple conditions, while JAK inhibitors show promise specifically for alopecia areata. The study emphasized the importance of individualized therapeutic approaches to enhance outcomes in hair loss management.
January 2025 in “Universitätsbibliothek Stuttgart” This article reviews the current challenges, innovations, and prospects of cosmetics designed to prevent hair loss and encourage hair growth, highlighting evolving technologies like gene therapy and the need for multidisciplinary approaches.
This review discusses potential cosmeceutical treatments for hair loss, including ingredients like procyanidins and isoflavones, but does not present new clinical outcomes; the authors highlight the promise of further research.
7 citations
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May 2013 in “PubMed” In this randomized, placebo-controlled study, the tested cosmetic ingredient containing Trifolium pratense flower extract and a biomimetic peptide increased anagen hair and improved the anagen/telogen ratio over four months in individuals with recessing hair.
January 2015 in “Hair therapy & transplantation” This review discusses natural and botanical products examined for treating alopecia and reports no clinical results; the authors note growing research interest in these treatments.
July 2022 in “Journal of Investigative Dermatology” The combination of a plant extract and a peptide can increase hair pigmentation and may reverse greying.
August 2016 in “Journal of Investigative Dermatology” This study observed that the osteopontin-derived peptide FOL-005 inhibited hair growth in human scalp skin models, contrary to its hair growth promotion in mice, supporting further clinical testing for excessive hair growth treatment.
4 citations
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December 2020 in “Scientific Reports” This study found that a mixture of plant extracts significantly improved skin barrier function, reduced inflammation, and exhibited anti-aging effects in human skin cells.
1 citations
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January 2013 in “Springer eBooks” Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
November 2025 in “Plant Science Today” This review explores the potential benefits of natural plant-based products for skin anti-aging, assessing effects on wrinkles, oxidative stress, pigmentation, and hydration, while also underscoring the importance of lifestyle factors such as diet, exercise, and sleep in skin health maintenance.
82 citations
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July 2022 in “Bioengineering & Translational Medicine” This review examines how biochemical and biophysical induction factors influence cell fate in tissue engineering and reports no new experimental results.
April 2018 in “Journal of Investigative Dermatology” This study found that acne lesions and nonlesional skin in mild-to-moderate acne patients showed significant Th17-skewing and increased antimicrobials, suggesting systemic targets like IL-17/IL-23/IL-36 could be therapeutic.
April 2018 in “Journal of Investigative Dermatology” This study found that Mentha suaveolens aqueous extract activated Nrf-2 and increased detoxifying enzyme expression in keratinocytes, providing protection against oxidative stress without cytotoxicity.
45 citations
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September 2012 in “Life Sciences” This study observed that Aconiti Ciliare Tuber extract may promote hair growth in mice by activating the Wnt/β-catenin signaling pathway.
44 citations
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March 2020 in “Antibiotics” The researchers reported that carnosic acid and carnosol, extracts from rosemary leaves, specifically inhibit S. aureus virulence expression, suggesting potential topical treatments for atopic dermatitis flares.
20 citations
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August 2015 in “International Journal of Molecular Medicine” This study found that human placental extract promoted hair growth and influenced cellular pathways in vitro and rat models, suggesting potential for future hair loss treatments.
7 citations
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March 2012 in “Journal of Investigative Dermatology” This study presents evidence that specific thymus-derived peptides affect human hair follicle growth, identifying thymulin as a potential hair growth stimulator despite interindividual response variations.
5 citations
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August 2018 This paper highlights the growing scientific interest in plant extracts for cosmetics due to their potential benefits, including antioxidant, antimicrobial, and protective properties, while emphasizing the need for quality and safety assessment to mitigate possible adverse reactions.