14 citations
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January 2020 in “Evidence-based Complementary and Alternative Medicine” This study found that a newly synthesized peptide from fermented Trapa japonica extract significantly promoted wound recovery and showed antiaging effects in skin cells and a clinical study, suggesting potential as a cosmetic product.
November 2022 in “Journal of Investigative Dermatology” This study found that sodium butyrate, a metabolite from the HF microbiome, significantly delayed catagen onset and promoted key physiological processes in cultured human hair follicles.
69 citations
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September 2013 in “American Journal of Alzheimer s Disease & Other Dementias®” This study found that a new peptide, Snakin-Z, from Ziziphus jujuba fruits, shows significant inhibitory effects on AChE and BChE enzymes and strong antioxidant activity, suggesting potential benefits for Alzheimer's disease treatment.
35 citations
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July 2010 in “The FEBS journal” In this study, researchers identified a highly reactive, isozyme-specific sequence for TGase 3, contributing to understanding its distinct functional role and activity distribution in the mouse epidermis.
February 2024 in “Brain research bulletin” This study observed that inhibiting androgenic activity during early postnatal development significantly decreased body weight in female rats by day 90, while affecting food intake and fat distribution in both sexes based on the inhibited testosterone metabolic pathway.
January 2024 in “Repositorio Digital de la Universidad Villanueva”
May 2023 in “Antioxidants” In this study, researchers found that supramolecular peptide self-assembling materials derived from Pacific oysters exhibit promising effects for skin wound healing in vitro and in vivo, demonstrating procoagulant, antioxidant, anti-inflammatory, and regenerative properties that suggest potential as a natural treatment option.
September 2018 in “Journal of Experimental & Biomedical Sciences” This study found that DK peptides demonstrated potent inhibition of 5α-reductase, suggesting they may be promising candidates for treating hair loss.
November 2007 in “Cancer Epidemiology and Prevention Biomarkers” In this study, PSA levels were significantly lower among African-American men with higher C-peptide levels and Caucasian men with higher HbA1c levels, suggesting a link between metabolic markers and prostate cancer detection.
November 2023 in “International Journal of Pharmaceutics” This study found that a new transdermal drug delivery system using globefish skin collagen peptides and dissolving microneedles effectively promoted hair regrowth in mice with androgenetic alopecia by reducing inflammation and enhancing vascularization.
April 2026 in “BMC Biotechnology” This study evaluated a novel synthetic cell-penetrating peptide, DualPep-ALO, finding it promotes hair growth by enhancing follicle cell proliferation, activating regenerative pathways, and reducing inflammation and oxidative stress in vitro and ex vivo, suggesting a promising new topical treatment for hair loss that rivals minoxidil.
2 citations
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March 2021 in “Andrologia” In this study, mesenchymal stem cell therapy improved erectile function in a rat model of diabetes-associated erectile dysfunction, and identified 15 hub genes potentially involved in the condition's development.
April 2018 in “Journal of Investigative Dermatology” In this animal study, the researchers found that DPP4 plays a crucial role in scar formation and wound-induced hair follicle neogenesis in mice, impacting regenerative repair.
2 citations
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November 2025 in “International Journal of Molecular Sciences” This review highlights that the skin microbiota plays a crucial role in wound healing, with beneficial microorganisms aiding tissue repair and opportunistic pathogens hindering it, potentially guiding future microbiome-targeted therapies.
1 citations
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June 2022 in “Gene reports” This study analyzed gene expression in Pashmina goats and identified key biological processes and molecular functions involved in long-fibre production, suggesting potential pathways for enhancing this trait in other goat breeds.
July 2019 in “Technology audit and production reserves” This research discusses the formulation of probiotic gel shampoos with whey peptides and plant extracts, highlighting their potential effectiveness and market feasibility in Ukraine.
17 citations
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April 2007 in “Kidney international” This study found that 1,25 dihydroxyvitamin D3 significantly increased the expression and activity of vasculoprotective natriuretic peptide receptor-A in cultured inner medullary collecting duct cells, suggesting a potential mechanistic role in cardiovascular and renal benefits.
May 2024 in “Archives of Dermatological Research” TAT-GILZ peptide promotes hair growth by boosting stem cell activity.
January 2026 in “International Journal of Molecular Sciences” This review suggests that topically applied peptides may offer a promising alternative for managing pain in chronic wounds, with additional potential benefits of anti-inflammatory and regenerative activities, but acknowledges the challenges of delivering these peptides across damaged skin barriers.
6 citations
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May 2022 in “Colloids and Surfaces B: Biointerfaces” This study found that oral administration of naturally safe active polypeptides from marine shellfish promoted scarless dermal wound healing in mice, potentially via effects on inflammation, fibroblast activity, and the "skin-gut" axis.
5 citations
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January 2017 in “Chalmers Publication Library (Chalmers University of Technology)” In this study, cubosome and hexosome carriers with antimicrobial peptides showed varied efficacy, with cubosomes protecting peptides from degradation and enhancing bactericidal effects in some cases, while hexosomes lacked antimicrobial activity.
1 citations
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December 2021 in “Development & Reproduction” This study found that FPR2 knockout mice experienced excessive hair loss and abnormal hair follicle structures, suggesting FPR2's protective role in hair regeneration through stem cell activity regulation.
This study found that peptides from Lablab purpureus, particularly fraction 2, demonstrated potential anticancer effects by exhibiting significant antioxidant and apoptotic activities, selectively inhibiting cancer cells with minimal impact on healthy cells.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that stimulating olfactory receptors in human hair follicles with Sandalore® increases antimicrobial activity by upregulating dermcidin production, potentially offering a novel approach for treating hair follicle diseases with bacterial issues.
April 2016 in “Journal of Investigative Dermatology” This study found that the peptide derivative beta-Ala-Pro-Dab-NHbenzyl may reduce wrinkles and sebum production in human skin by inhibiting dipeptidyl peptidase 4, suggesting potential for acne and skin inflammation treatment.
66 citations
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July 2007 in “Journal of Molecular Medicine” This study in mice demonstrated that stress or nerve growth factor injection increases sensory neuron activity related to skin innervation, suggesting a strong connection between stress perception and neurogenic skin inflammation.
1 citations
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November 2022 in “International journal of trichology” In this case study, a 25-year-old female with premature hair graying achieved over 90% conversion of gray hair to black hair after 5 months of treatment with a topical peptide solution and hair supplements.
In this study, researchers investigated the impact of a bioactive peptide derived from amphibians on hair follicle regeneration in diabetic skin, focusing on its potential to enhance wound healing and reduce infection risk.
April 2018 in “Journal of Investigative Dermatology” In this study, researchers observed that alopecia areata patients showed higher Th1 and Th2 responses against specific melanogenesis-related protein epitopes, suggesting a role in disease activity and potential targets for diagnostics and therapies.
October 2010 in “Reproductive Biomedicine Online” This study reported that MALDI-TOF Mass Spectrometry profiling demonstrated nearly 100% sensitivity and specificity in detecting adenomyosis and leiomyoma, revealing potential peptide markers for these conditions.