21 citations
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November 2019 in “Molecular & Cellular Proteomics” This study found that citrullinated proteins, which are implicated in rheumatoid arthritis, were abundant in outer membrane vesicles from Porphyromonas gingivalis but nearly absent in mutants, validating their approach to citrullinated peptide identification.
20 citations
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January 1995 in “Journal of Dermatological Science” This study found that topical application of cyclosporin A and FK506 induces new hair growth in mice, while ascomycin and rapamycin do not, suggesting hair induction is not due to immunosuppression.
17 citations
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April 2007 in “Kidney international” This study found that 1,25 dihydroxyvitamin D3 significantly increased the expression and activity of vasculoprotective natriuretic peptide receptor-A in cultured inner medullary collecting duct cells, suggesting a potential mechanistic role in cardiovascular and renal benefits.
15 citations
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June 2018 in “Food Reviews International” This review discusses the potential benefits of pumpkin seed oil for men's health, particularly in conditions such as benign prostatic hyperplasia, overactive bladder, and androgenic alopecia, but reports no new clinical results.
13 citations
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May 2021 in “FASEB bioAdvances” This review discusses plant-based alternatives to retinoids for dermal antiaging and hair health, highlighting roles for cytokinins and phytoestrogens and reports no new results.
12 citations
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June 2025 in “Gut Microbes” This study developed BroadAMP-GPT, a computational-experimental framework, to discover new antimicrobial peptides, identifying candidates effective against multidrug-resistant pathogens. Notably, AMP_S13 showed strong stability, low toxicity, and efficacy in infection models, highlighting the platform's potential in combating antimicrobial resistance.
11 citations
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January 2015 in “Skin pharmacology and physiology” In this study, oral collagen peptides increased certain gene expressions related to epidermis development and the hair cycle in hairless mice skin, suggesting potential links to hair health.
10 citations
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November 2023 in “Frontiers in Pharmacology” In this study, researchers developed a self-assembling hydrogel called RADA-PDGF2 and found it to accelerate wound closure in a mouse model due to its pro-proliferative and pro-migratory properties, without causing cytotoxicity or immunogenicity.
9 citations
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August 2018 in “Biomedical dermatology” This study found that topical administration of the TGFβ mimetic peptide DPS-1 stimulated hair growth in mice by promoting HDP cell proliferation and enhancing hair follicle morphology.
9 citations
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November 2019 in “Scientific reports” This study isolated a bioactive peptide from Trapa japonica fruit and found that it may protect human dermal papilla cells from DHT-induced stress, suggesting potential for biomedical applications.
8 citations
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January 2016 in “Annals of Dermatology” This study found that the ALAVAX complex, containing 5-ALA and GHK peptide, may increase hair count in male pattern hair loss patients over 6 months without adverse events.
8 citations
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December 2018 in “Journal of Dermatological Treatment” This study found that a PRP-like cosmetic product called TR-M-PRP plus significantly improved hair growth in individuals with alopecia areata over three months, as measured by the SALT score, suggesting it could be a safer alternative to traditional PRP treatments.
8 citations
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June 2004 in “Journal of Investigative Dermatology” Certain peptides can prevent hair loss in young rats caused by a cancer drug.
7 citations
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March 2012 in “Journal of Investigative Dermatology” This study presents evidence that specific thymus-derived peptides affect human hair follicle growth, identifying thymulin as a potential hair growth stimulator despite interindividual response variations.
6 citations
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April 2025 in “Food Bioscience” This study found that fish scale collagen peptide significantly promoted wound healing in mice, with the <1 kDa fractions enhancing collagen synthesis and reducing inflammation, suggesting potential clinical benefits.
6 citations
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January 2024 in “Frontiers in Bioengineering and Biotechnology” This study developed a smart PVA-TPE/HA-AMP/SF/ALG wound dressing that shows promise in infected wound healing by providing bacterial resistance, promoting cell proliferation, and modulating inflammation through various signaling pathways, potentially reducing scar formation.
6 citations
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February 2023 in “Journal of nanobiotechnology” In this study, HA-P5, a nanoparticle derived from peptide and polysaccharide conjugation, effectively reduced acne lesions and sebum production by inhibiting specific receptors in cells, without triggering unfavorable reactions compared to a commercial inhibitor, highlighting HA-P5's potential as a novel acne treatment.
6 citations
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May 2022 in “Colloids and Surfaces B: Biointerfaces” This study found that oral administration of naturally safe active polypeptides from marine shellfish promoted scarless dermal wound healing in mice, potentially via effects on inflammation, fibroblast activity, and the "skin-gut" axis.
6 citations
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August 2015 in “Acta histochemica” In this study, lysozyme was found to promote vibrissae follicle growth in vitro by enhancing the hair-inductive capacity of dermal papilla cells.
5 citations
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January 2017 in “Chalmers Publication Library (Chalmers University of Technology)” In this study, cubosome and hexosome carriers with antimicrobial peptides showed varied efficacy, with cubosomes protecting peptides from degradation and enhancing bactericidal effects in some cases, while hexosomes lacked antimicrobial activity.
4 citations
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October 2025 in “Molecules” This study concluded that extracts from fermented pumpkin peel and pulp, processed with Lactobacillus strains and kombucha, may serve as multifunctional cosmetic ingredients, offering antioxidant protection, anti-aging, and skin regeneration benefits by demonstrating cytoprotective effects and reducing inflammatory cytokines in cell assays.
4 citations
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November 2024 in “International Journal of Biological Macromolecules” In this study, the researchers developed a cellulose nanofiber-based scaffold containing sitagliptin and zinc sulfide nanoparticles, which promoted scarless healing and hair follicle regeneration in rats by targeting DPP4+ fibroblasts, suggesting a novel approach for improved wound healing and skin regeneration.
4 citations
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June 2022 in “Journal of Cosmetic Dermatology” This study suggests that dermal fibroblast-conditioned medium containing multi-peptide factors may stimulate hair growth by enhancing growth factor expression and β-catenin regulation in hair follicle cells.
4 citations
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May 2022 in “Journal of Drug Delivery Science and Technology” This research observed that nanoliposomes delivering a combination of bioactive peptides significantly promoted hair growth in vitro and in vivo by enhancing the proliferation and function of hair growth-targeted cells in C57BL/6 mice, suggesting a promising approach for treating androgenetic alopecia.
3 citations
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March 2016 in “Journal of Cosmetic Dermatology” This study found that the penta-peptide Gly-Pro-Ile-Gly-Ser increased the proportion of thick hair and improved baldness appearance in Japanese men with androgenetic alopecia.
2 citations
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November 2023 in “Bioactive materials” The researchers reported that a newly developed ionic liquid-based microemulsion significantly improved the local delivery of copper peptides in mice, enhancing hair growth-related factor activation while offering a safer, non-invasive alternative to existing treatments for hair loss.
1 citations
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August 2025 in “Bioengineering” In this study, the combination of full-thickness skin column grafts and the TSN6 peptide improved wound healing quality in pigs by enhancing epidermal maturation compared to other treatments.
1 citations
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January 2022 in “Journal of Pharmaceutical Sciences” This study developed a stable, cosmetically appealing formulation for the topical delivery of the peptide FOL-005, enhancing skin permeation and maintaining stability by keeping the peptide solid and in a water-free environment with particle sizes under 10 µm.
1 citations
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January 2022 1 citations
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December 2021 in “Development & Reproduction” This study found that FPR2 knockout mice experienced excessive hair loss and abnormal hair follicle structures, suggesting FPR2's protective role in hair regeneration through stem cell activity regulation.