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February 2024 in “Journal of the European Academy of Dermatology and Venereology” Certain genetic factors may contribute to frontal fibrosing alopecia in Brazil.
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March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that AtCEPs in Arabidopsis thaliana play a role in controlling root hair growth by processing EXT proteins, with NAC1 acting to regulate their expression and influence elongation.
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February 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that Peperomia pellucida extract may promote hair growth, improve male libido and fertility, and support renal cell health.
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January 2020 in “Gastronomica The Journal of Food and Culture” This article reviews the cultural history and changing scientific perceptions of peppercorn as a "numbing spice," focusing on its historical, medical, and literary significance, but provides no new research findings.
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October 2017 This study found that topical gel containing ethanolic extract of Peperomia pellucida increased hair length in rabbits, but did not significantly impact hair mass compared to control treatments.
February 2024 in “Frontiers in plant science” This study found that Plant Elicitor Peptides enhance root hair growth through a mechanism independent of their known receptors, with PROPEP2 playing a key role in this process by influencing gene expression related to root hair formation.
In this study, researchers investigated the impact of a bioactive peptide derived from amphibians on hair follicle regeneration in diabetic skin, focusing on its potential to enhance wound healing and reduce infection risk.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This narrative literature review by Lustrao synthesizes existing research on six botanical ingredients used in Lustrao Hair Regrowth Oil, noting varying evidence levels with rosemary oil showing the clearest human clinical support for hair growth, particularly against minoxidil.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This narrative literature review by Lustrao examines the existing research on six botanical ingredients in their Hair Regrowth Oil, finding varied evidence levels and highlighting rosemary oil's strong human clinical support for hair growth compared to minoxidil.
July 2026 in “International Journal of Health Science” In this narrative review, researchers found that biomimetic peptides, which mimic natural biological functions, show potential in improving hair density and thickness in people with alopecia, although more robust clinical studies are needed to confirm their efficacy for clinical use.
June 2026 in “Drug Design Development and Therapy” This review critically examines recent progress in peptide-based treatments for pancreatic disorders, including tools and strategies for pancreatitis, diabetes, and pancreatic cancer, highlighting advancements in drug design and preclinical efficacy, while also detailing ongoing clinical trials and future directions in precision medicine.
May 2026 in “Commagene Journal of Biology” This review found that anti-aging peptides show promise in cosmeceuticals due to their targeted actions to rejuvenate skin, but challenges like peptide stability, penetration, and limited clinical data limit their current effectiveness.
May 2026 in “SKIN The Journal of Cutaneous Medicine” This study suggests that a proprietary nutraceutical supplement gummy and peptide serum regimen may be safe and effective for improving hair growth and density in females with pattern hair loss.
April 2026 in “Biomedicines” This review highlights advancements in peptide-based treatments for hair loss, outlining their potential benefits and limitations, and suggests that combining peptide formulations with nanosystems may overcome existing challenges in hair regrowth therapies according to this source.
March 2026 in “Bioconjugate Chemistry” This review highlights the potential of peptide-based PROTACs (pPROTACs) in expanding the target range of protein degraders beyond small-molecule limitations, particularly for undruggable proteins, by utilizing advances in design, conjugation, and bioPROTAC technology.
January 2026 in “RIGGS Journal of Artificial Intelligence and Digital Business” This study analyzed the formulation and stability of pomade containing peppermint oil and minoxidil, determining that a particular formulation with 1% paraffin yielded optimal physical and stability characteristics for promoting hair growth, making it the best choice among the tested options.
January 2026 in “International Journal of Molecular Sciences” This review suggests that topically applied peptides may offer a promising alternative for managing pain in chronic wounds, with additional potential benefits of anti-inflammatory and regenerative activities, but acknowledges the challenges of delivering these peptides across damaged skin barriers.
January 2026 in “Biomacromolecules” This study developed a peptide-based topical delivery system that enhanced hair growth with reduced systemic exposure to finasteride, showing efficacy comparable to 5% minoxidil in vivo while using significantly less finasteride than oral doses.
January 2026 in “AIP conference proceedings” December 2025 in “Rapid Communications in Mass Spectrometry” This study found that pepsin digestion was more effective than trypsin at identifying keratin-associated proteins in human hair shafts and confirmed that trypsin introduced a bias in the analysis of protein composition that pepsin can correct.
November 2025 in “Journal of Investigative Dermatology” This study identified nine pathogenic variants in the PADI3 gene and variants in the S100A3 and TCHH genes in patients with central centrifugal cicatricial alopecia, suggesting a broader genetic basis for the disease and potential targets for genetic testing and therapies.
November 2025 in “PubMed” This study identified nine pathogenic variants in the PADI3 gene, and variants in the S100A3 and TCHH genes, which may disrupt protein function and contribute to central centrifugal cicatricial alopecia.
May 2025 in “Journal of Dispersion Science and Technology” This study reported that a novel SMEDDS formulation of PPO demonstrated better permeation and improved hair growth compared to a marketed formulation in tests for managing androgenetic alopecia, with further exploration suggested.
March 2025 in “Journal of Cutaneous and Aesthetic Surgery” In this study, three different hair serums were tested for their impact on Telogen effluvium in adult females, finding all effective in reducing hair shedding, with the cytokine-based serum showing the most significant improvement, reducing hair fall by 54.6% without adverse effects.
January 2025 in “Pharmaceuticals” This review discusses the potential of peptide-based hydrogels as biomaterials for treating chronic wounds and reports no new clinical findings.
January 2025 in “Yonsei Medical Journal” The study found that a novel mixture of mastic gum and peppermint extract increased hair growth and gloss in C57BL/6 mice, showing potential as a botanical alternative for promoting hair health.
January 2025 in “Journal of Applied Pharmaceutical Science” This study examined the effectiveness of peppermint essential oil formulated into a nanoliposome gel for enhancing hair growth, finding that this preparation increased hair growth in male Sprague Dawley rats without causing irritation, suggesting it may improve delivery of these active ingredients.
November 2024 in “Journal of Investigative Dermatology” Genetic changes in specific proteins contribute to hair loss in some women of African descent.
July 2024 in “International journal of agriculture and food sciences research.” This study found that a hair conditioner using peptides from Pneumatophorus japonicus heads improved damaged hair's structure, gloss, and smoothness more effectively than a commercial wheat protein conditioner by increasing amino acid content and interacting with hair keratin.
July 2024 in “Jurnal Adiguna Pengabdian Masyarakat.” This study reports that a community program in Desa Cibiru Wetan led to a significant increase in knowledge about utilizing peppermint leaves from TOGA cultivation as an ingredient in hair masks, which may enhance local economic opportunities.