research Dutasteride
Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
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research A Mouse Model of Androgenetic Alopecia
Mice with human gene experienced hair loss when treated with DHT.
research Pseudoacromegaly Induced by the Long-Term Use of Minoxidil
Long-term minoxidil use can cause pseudoacromegaly, but stopping it improves symptoms.
research Prevalence of CYP21 Mutations and IRS1 Variant Among Women With Polycystic Ovary Syndrome and Adrenal Androgen Excess
Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.
research Tofacitinib Therapy for Children with Severe Alopecia Areata
Tofacitinib may help treat severe childhood alopecia areata, but risks require careful consideration.
research Alopecias in Lupus Erythematosus
Different types of hair loss in lupus need careful diagnosis for proper treatment.
research Surrogate End-Points or Primary Outcomes in Clinical Trials in Women with Polycystic Ovary Syndrome?
The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
research Decreased Fertility in Male Rats Administered the 5α-Reductase Inhibitor, Finasteride, Due to Deficits in Copulatory Plug Formation
Finasteride reduces male rat fertility by causing issues with copulatory plug formation.
research Prognosis, Treatment, and Disease Outcomes in Frontal Fibrosing Alopecia: A Retrospective Review of 92 Cases
Most patients with frontal fibrosing alopecia stabilized with treatment, especially younger ones, using intralesional corticosteroids and tacrolimus.
research Scalp Dysesthesia Related to Cervical Spine Disease
Most women with weird scalp feelings had neck spine problems, and some got better with gabapentin treatment.
research Development of a Health-Related Quality of Life Questionnaire for Women with Androgenetic Alopecia
WAA-QOL measures impact of hair loss on women's well-being.
research Modeling of Chronic Radiation-Induced Cystitis in Mice
Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
research Pharmacologic Modulation of Sebaceous Gland Activity: Mechanisms and Clinical Applications
The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
research Variation in Human Hair Ultrastructure Among Three Biogeographic Populations
Different populations have distinct hair structures related to their ancestry.
research Cystathionine Beta-Synthase-Deficient Mice Thrive on a Low-Methionine Diet
Mice with CBS deficiency are healthier on a low-methionine diet.
research Characterization and Quantification of Wound-Induced Hair Follicle Neogenesis Using In Vivo Confocal Scanning Laser Microscopy
In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.
research Anisotrichosis: A Novel Term to Describe Pattern Alopecia
The document suggests "anisotrichosis" as a new term for hair thickness variation in common baldness.
research Androgen Receptor in Rat Liver: Characterization and Separation from a Male-Specific Estrogen-Binding Protein
Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.
research Commentary: Treatment of Lichen Planopilaris
Effective treatments for lichen planopilaris are unclear due to inconsistent results and a lack of strong research evidence.
research Economic Analysis of Finasteride: A Model-Based Approach Using Data from the Proscar Long-Term Efficacy and Safety Study
Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.
research Contact Dermatitis in Reaction to 2% Topical Minoxidil Solution
Minoxidil solution can cause skin irritation and allergies in some users.
research Contraceptive Use in Acne
Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.
research Exfoliative Cutaneous Lupus Erythematosus in German Shorthaired Pointer Dogs: Disease Development, Progression, and Evaluation of Three Immunomodulatory Drugs (Ciclosporin, Hydroxychloroquine, and Adalimumab) in a Controlled Environment
Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.
research Cronkhite-Canada Syndrome: Report of an Unusual Case
The report described a unique case of Cronkhite-Canada syndrome with unusual polyps and an association with multiple myeloma.
research Fluoride Toothpaste: A Cause of Perioral Dermatitis
Stopping fluoride toothpaste use might improve perioral dermatitis.
research Female Adolescent Hair Disorders
Quick treatment of hair disorders in teenage girls is important because of the emotional effects.
research A Variant of the Glucocorticoid Receptor Gene Is Not Associated with Adrenal Androgen Excess in Women with Polycystic Ovary Syndrome
The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.
research Elastic Staining Versus Fluorescent and Polarized Microscopy in the Diagnosis of Alopecia
EVG staining is the most reliable method for diagnosing alopecia.
research Osteopontin Gene Is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner
The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
research Two-Photon Microscopy for Intracutaneous Imaging of Stem Cell Activity in Mice
Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.