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Quick, selective detection of tadalafil and finasteride in human plasma developed.

Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Finasteride is considered the best treatment for hair loss, despite side effects.

To prevent and treat Hair-thread tourniquet syndrome in infants, keep a close eye on their limbs, manage maternal hair loss, and educate parents and healthcare providers.

The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.

A hair tightly wrapped around a toddler's toe caused severe crying and was treated by surgery.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

Horse skin diseases are complex to manage and often require a biopsy for accurate diagnosis and treatment.

Hormone therapy increases facial and body hair in transgender men, while hair removal improves well-being in transgender women, but cost is a barrier as insurance often doesn't cover it. Dermatologists can use various treatments for these hair issues.

The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.

Baldness, especially at the front, may lower the risk of testicular cancer by 31%, but its link to prostate cancer is unclear.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

The conclusion is that off-label drug use can lead to important medical discoveries and improve patient care.

Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.

Lichen planopilaris in men often involves scalp redness and itching, with some also having hair loss, mucosal lichen planus, or thyroid disease, and treatment improved symptoms in nearly half of the cases.

Flutamide-induced hypospadias in rats slows down early wound healing.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Educating healthcare workers and parents about hair toe tourniquets can help prevent serious complications.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.

A 25-year-old Malay fireman had skin bumps on his neck that were removed successfully after other treatments failed.

Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.

Finasteride treats hair loss but may cause low libido, erectile issues, and depression.